Additive Effects of Dorzagliatin and Glucagon-Like Peptide 1 Receptor Agonism in a Novel Mouse Model of GCK-MODY and in Obese db/db Mice.

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Title: Additive Effects of Dorzagliatin and Glucagon-Like Peptide 1 Receptor Agonism in a Novel Mouse Model of GCK-MODY and in Obese db/db Mice.
Authors: Salazar S; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada., Delgadillo-Silva LF; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada., Carapeto P; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada., Kenfaoui MM; Department of Biochemistry and Molecular Medicine, Université de Montréal, Quebec, Canada., Dakessian K; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada., Melhem R; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada., Provencher-Girard A; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada., Ostinelli G; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada., Turgeon J; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada., Kaci I; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada.; Département de Médecine, Université de Montréal, Montréal, Quebec, Canada., Migneault F; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada.; Département de Microbiologie, Infectiologie et Immunologie, Faculté de Médecine, Université de Montréal, Montréal, Quebec, Canada., Huising MO; Department of Neurobiology, Physiology and Behavior, College of Biological Sciences, University of California, Davis, Davis, CA.; Department of Physiology and Membrane Biology, School of Medicine, University of California, Davis, Davis, CA., Hébert MJ; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada.; Département de Médecine, Université de Montréal, Montréal, Quebec, Canada., Chaker-Margot M; Department of Biochemistry and Molecular Medicine, Université de Montréal, Quebec, Canada., Rutter GA; Research Center of the Hospital Center of the University of Montreal and University of Montreal, Quebec, Canada.; Section of Cell Biology and Functional Genomics, Division of Diabetes, Endocrinology and Metabolism, Faculty of Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, Hammersmith Hospital, London, U.K.; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Lee Kong Chian School of Medicine, Nanyang Technological College, Singapore.
Source: Diabetes [Diabetes] 2026 Jan 01; Vol. 75 (1), pp. 99-114.
Publication Type: Journal Article
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1939-327X
DOI:10.2337/db25-0520