Acinar-specific loss of activating transcription factor 3 restricts KRASG12D mediated transcriptional changes and PanIN progression.
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| Title: | Acinar-specific loss of activating transcription factor 3 restricts KRASG12D mediated transcriptional changes and PanIN progression. |
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| Authors: | Martin MB; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada., Mousavi F; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada., Goebel G; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada., Di Stasi D; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada., Mano A; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada., Glogov A; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Zhao L; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Di Guglielmo G; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Shooshtari P; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Children's Health Research Institute, London Health Sciences Centre Research Institute, London, ON, Canada.; Department of Paediatrics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada., Pin CL; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. cpin@uwo.ca.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada. cpin@uwo.ca.; Children's Health Research Institute, London Health Sciences Centre Research Institute, London, ON, Canada. cpin@uwo.ca.; Department of Paediatrics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. cpin@uwo.ca.; Department of Oncology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. cpin@uwo.ca. |
| Source: | Cell death discovery [Cell Death Discov] 2025 Nov 06; Vol. 11 (1), pp. 503. Date of Electronic Publication: 2025 Nov 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| FullText | Links: – Type: pdflink Text: Availability: 1 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41198649 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Acinar-specific loss of activating transcription factor 3 restricts KRAS<superscript>G12D</superscript> mediated transcriptional changes and PanIN progression. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Martin+MB%22">Martin MB</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Mousavi+F%22">Mousavi F</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Goebel+G%22">Goebel G</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Di+Stasi+D%22">Di Stasi D</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Mano+A%22">Mano A</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Glogov+A%22">Glogov A</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Zhao+L%22">Zhao L</searchLink>; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Di+Guglielmo+G%22">Di Guglielmo G</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Shooshtari+P%22">Shooshtari P</searchLink>; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.; Children's Health Research Institute, London Health Sciences Centre Research Institute, London, ON, Canada.; Department of Paediatrics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Pin+CL%22">Pin CL</searchLink>; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. cpin@uwo.ca.; Cancer Research Laboratory Program, London Health Sciences Research Institute and Verspeeten Family Cancer Centre, London, ON, Canada. cpin@uwo.ca.; Children's Health Research Institute, London Health Sciences Centre Research Institute, London, ON, Canada. cpin@uwo.ca.; Department of Paediatrics, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. cpin@uwo.ca.; Department of Oncology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada. cpin@uwo.ca. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2025 Nov 06; Vol. 11 (1), pp. 503. <i>Date of Electronic Publication: </i>2025 Nov 06. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41198649 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41420-025-02777-2 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 503 Titles: – TitleFull: Acinar-specific loss of activating transcription factor 3 restricts KRASG12D mediated transcriptional changes and PanIN progression. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Martin MB – PersonEntity: Name: NameFull: Mousavi F – PersonEntity: Name: NameFull: Goebel G – PersonEntity: Name: NameFull: Di Stasi D – PersonEntity: Name: NameFull: Mano A – PersonEntity: Name: NameFull: Glogov A – PersonEntity: Name: NameFull: Zhao L – PersonEntity: Name: NameFull: Di Guglielmo G – PersonEntity: Name: NameFull: Shooshtari P – PersonEntity: Name: NameFull: Pin CL IsPartOfRelationships: – BibEntity: Dates: – D: 06 M: 11 Text: 2025 Nov 06 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 2058-7716 Numbering: – Type: volume Value: 11 – Type: issue Value: 1 Titles: – TitleFull: Cell death discovery Type: main |
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