Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment.

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Title: Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment.
Authors: Yauk CL; Department of Biology, University of Ottawa, Ottawa, ON, Canada., Lynch AM; Genetics and Investigative Toxicology, GSK, Stevenage, United Kingdom., Dobrovolsky VN; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Schuler M; Pfizer Research, Development and Medical, Groton, CT, USA., Smith-Roe SL; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA., Fitzgerald D; Independent Researcher (formerly TwinStrand Biosciences), Seattle, WA, USA., Higgins J; Independent Researcher (formerly TwinStrand Biosciences), Seattle, WA, USA., Honarvar N; BASF SE, Ludwigshafen, Germany., Le Curieux F; European Chemicals Agency, Helsinki, Finland., Matsumura S; R&D, Safety Science Research, Kao Corporation, Kanagawa, Japan., Minocherhomji S; Eli Lilly and Company, Indianapolis, IN, USA., Recio L; ScitoVation, Durham, NC, USA., Salk JJ; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, USA., Sugiyama KI; Division of Genome Safety Science, National Institute of Health Sciences, Kanagawa, Japan., Suzuki T; Division of Genome Safety Science, National Institute of Health Sciences, Kanagawa, Japan., Wills JW; Genetics and Investigative Toxicology, GSK, Stevenage, United Kingdom., Marchetti F; Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada. Electronic address: Francesco.marchetti@hc-sc.gc.ca.
Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2026 Jan; Vol. 164, pp. 105985. Date of Electronic Publication: 2025 Nov 08.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-0295
DOI:10.1016/j.yrtph.2025.105985