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Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment.

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Title: Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment.
Authors: Yauk CL; Department of Biology, University of Ottawa, Ottawa, ON, Canada., Lynch AM; Genetics and Investigative Toxicology, GSK, Stevenage, United Kingdom., Dobrovolsky VN; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA., Schuler M; Pfizer Research, Development and Medical, Groton, CT, USA., Smith-Roe SL; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA., Fitzgerald D; Independent Researcher (formerly TwinStrand Biosciences), Seattle, WA, USA., Higgins J; Independent Researcher (formerly TwinStrand Biosciences), Seattle, WA, USA., Honarvar N; BASF SE, Ludwigshafen, Germany., Le Curieux F; European Chemicals Agency, Helsinki, Finland., Matsumura S; R&D, Safety Science Research, Kao Corporation, Kanagawa, Japan., Minocherhomji S; Eli Lilly and Company, Indianapolis, IN, USA., Recio L; ScitoVation, Durham, NC, USA., Salk JJ; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, USA., Sugiyama KI; Division of Genome Safety Science, National Institute of Health Sciences, Kanagawa, Japan., Suzuki T; Division of Genome Safety Science, National Institute of Health Sciences, Kanagawa, Japan., Wills JW; Genetics and Investigative Toxicology, GSK, Stevenage, United Kingdom., Marchetti F; Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada. Electronic address: Francesco.marchetti@hc-sc.gc.ca.
Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2026 Jan; Vol. 164, pp. 105985. Date of Electronic Publication: 2025 Nov 08.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Application of error-corrected sequencing technologies for in vivo regulatory mutagenicity assessment.
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  Data: <searchLink fieldCode="AU" term="%22Yauk+CL%22">Yauk CL</searchLink>; Department of Biology, University of Ottawa, Ottawa, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Lynch+AM%22">Lynch AM</searchLink>; Genetics and Investigative Toxicology, GSK, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Dobrovolsky+VN%22">Dobrovolsky VN</searchLink>; National Center for Toxicological Research, US Food and Drug Administration, Jefferson, AR, USA.<br /><searchLink fieldCode="AU" term="%22Schuler+M%22">Schuler M</searchLink>; Pfizer Research, Development and Medical, Groton, CT, USA.<br /><searchLink fieldCode="AU" term="%22Smith-Roe+SL%22">Smith-Roe SL</searchLink>; Division of Translational Toxicology, National Institute of Environmental Health Sciences, Research Triangle Park, NC, USA.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+D%22">Fitzgerald D</searchLink>; Independent Researcher (formerly TwinStrand Biosciences), Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Higgins+J%22">Higgins J</searchLink>; Independent Researcher (formerly TwinStrand Biosciences), Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Honarvar+N%22">Honarvar N</searchLink>; BASF SE, Ludwigshafen, Germany.<br /><searchLink fieldCode="AU" term="%22Le+Curieux+F%22">Le Curieux F</searchLink>; European Chemicals Agency, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Matsumura+S%22">Matsumura S</searchLink>; R&D, Safety Science Research, Kao Corporation, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Minocherhomji+S%22">Minocherhomji S</searchLink>; Eli Lilly and Company, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Recio+L%22">Recio L</searchLink>; ScitoVation, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Salk+JJ%22">Salk JJ</searchLink>; Division of Hematology and Oncology, Department of Medicine, University of Washington, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Sugiyama+KI%22">Sugiyama KI</searchLink>; Division of Genome Safety Science, National Institute of Health Sciences, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Suzuki+T%22">Suzuki T</searchLink>; Division of Genome Safety Science, National Institute of Health Sciences, Kanagawa, Japan.<br /><searchLink fieldCode="AU" term="%22Wills+JW%22">Wills JW</searchLink>; Genetics and Investigative Toxicology, GSK, Stevenage, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Marchetti+F%22">Marchetti F</searchLink>; Environmental Health Science and Research Bureau, Health Canada, Ottawa, ON, Canada. Electronic address: Francesco.marchetti@hc-sc.gc.ca.
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  Data: <searchLink fieldCode="JN" term="%228214983%22">Regulatory toxicology and pharmacology : RTP</searchLink> [Regul Toxicol Pharmacol] 2026 Jan; Vol. 164, pp. 105985. <i>Date of Electronic Publication: </i>2025 Nov 08.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8214983 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-0295 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202732300%22">02732300 </searchLink><i>NLM ISO Abbreviation: </i>Regul Toxicol Pharmacol <i>Subsets: </i>MEDLINE
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