Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107.

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Title: Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107.
Authors: Schmitz J; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Bartkowiak AL; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Rose M; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; Institute of Pathology, University Hospital, RWTH Aachen University, Germany.; Institute of Pathology, University Hospital, University of Ulm, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany., Kolks N; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Petzsch P; Genomics and Transcriptomics Laboratory (GTL), Biological and Medical Research Center (BMFZ), Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany., Solanki V; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands., Stoffel A; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany., Faßbender B; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany., Lepping L; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Volkamer J; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Köhrer K; Genomics and Transcriptomics Laboratory (GTL), Biological and Medical Research Center (BMFZ), Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany., Seifert M; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany., Mahmoudi T; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands.; Department of Pathology, Erasmus University Medical Center Rotterdam, The Netherlands., Zuiverloon TCM; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands., Niegisch G; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany., Hoffmann MJ; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany.
Source: Molecular oncology [Mol Oncol] 2026 Mar; Vol. 20 (3), pp. 779-803. Date of Electronic Publication: 2025 Nov 11.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1878-0261
DOI:10.1002/1878-0261.70148