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Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107.

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Title: Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107.
Authors: Schmitz J; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Bartkowiak AL; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Rose M; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; Institute of Pathology, University Hospital, RWTH Aachen University, Germany.; Institute of Pathology, University Hospital, University of Ulm, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany., Kolks N; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Petzsch P; Genomics and Transcriptomics Laboratory (GTL), Biological and Medical Research Center (BMFZ), Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany., Solanki V; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands., Stoffel A; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany., Faßbender B; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany., Lepping L; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Volkamer J; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany., Köhrer K; Genomics and Transcriptomics Laboratory (GTL), Biological and Medical Research Center (BMFZ), Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany., Seifert M; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany., Mahmoudi T; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands.; Department of Pathology, Erasmus University Medical Center Rotterdam, The Netherlands., Zuiverloon TCM; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands., Niegisch G; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany., Hoffmann MJ; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany.
Source: Molecular oncology [Mol Oncol] 2026 Mar; Vol. 20 (3), pp. 779-803. Date of Electronic Publication: 2025 Nov 11.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons, Inc Country of Publication: United States NLM ID: 101308230 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0261 (Electronic) Linking ISSN: 15747891 NLM ISO Abbreviation: Mol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107.
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  Data: <searchLink fieldCode="AU" term="%22Schmitz+J%22">Schmitz J</searchLink>; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Bartkowiak+AL%22">Bartkowiak AL</searchLink>; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Rose+M%22">Rose M</searchLink>; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; Institute of Pathology, University Hospital, RWTH Aachen University, Germany.; Institute of Pathology, University Hospital, University of Ulm, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany.<br /><searchLink fieldCode="AU" term="%22Kolks+N%22">Kolks N</searchLink>; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Petzsch+P%22">Petzsch P</searchLink>; Genomics and Transcriptomics Laboratory (GTL), Biological and Medical Research Center (BMFZ), Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Solanki+V%22">Solanki V</searchLink>; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Stoffel+A%22">Stoffel A</searchLink>; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Faßbender+B%22">Faßbender B</searchLink>; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Lepping+L%22">Lepping L</searchLink>; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Volkamer+J%22">Volkamer J</searchLink>; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Köhrer+K%22">Köhrer K</searchLink>; Genomics and Transcriptomics Laboratory (GTL), Biological and Medical Research Center (BMFZ), Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Seifert+M%22">Seifert M</searchLink>; Department of Haematology, Oncology and Clinical Immunology, University Hospital Düsseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Mahmoudi+T%22">Mahmoudi T</searchLink>; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands.; Department of Pathology, Erasmus University Medical Center Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zuiverloon+TCM%22">Zuiverloon TCM</searchLink>; Department of Urology, Erasmus MC Cancer Institute, Erasmus University Medical Center Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Niegisch+G%22">Niegisch G</searchLink>; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+MJ%22">Hoffmann MJ</searchLink>; Department of Urology, Medical Faculty and University Hospital Duesseldorf, Heinrich-Heine-University Duesseldorf, Germany.; Center for Integrated Oncology (CIO) Duesseldorf, CIO Aachen Bonn Cologne Duesseldorf, Germany.; German Study Group of Bladder Cancer (DFBK e.V.), Germany.
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  Data: <searchLink fieldCode="JN" term="%22101308230%22">Molecular oncology</searchLink> [Mol Oncol] 2026 Mar; Vol. 20 (3), pp. 779-803. <i>Date of Electronic Publication: </i>2025 Nov 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22John+Wiley+%26+Sons%2C+Inc%22">John Wiley & Sons, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101308230 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-0261 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215747891%22">15747891 </searchLink><i>NLM ISO Abbreviation: </i>Mol Oncol <i>Subsets: </i>MEDLINE
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