Increasing inflammatory biomarkers are associated with mortality in critically ill COVID-19 patients despite anti-inflammatory treatment.

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Bibliographic Details
Title: Increasing inflammatory biomarkers are associated with mortality in critically ill COVID-19 patients despite anti-inflammatory treatment.
Authors: Daenen K; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. k.daenen@erasmusmc.nl.; Department of Viroscience, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands. k.daenen@erasmusmc.nl., Rizopoulos D; Department of Biostatistics, Erasmus University Medical Center, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands., Dalm VASH; Department of Immunology, Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands.; Department of Internal Medicine, Division of Allergy & Clinical Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands., Huijben JA; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands., Stoof SCM; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands., Nagtzaam NMA; Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands., Dik WA; Laboratory Medical Immunology, Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.; Laboratory Medical Immunology, Reinier Haga Medisch Diagnostisch Centrum (RHMDC), Delft, The Netherlands., Swagemakers SMA; Department of Pathology & Clinical Bioinformatics, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., van der Spek PJ; Department of Pathology & Clinical Bioinformatics, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands., Tong-Minh K; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.; Department of Viroscience, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands., Mersha DGA; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.; Department of Viroscience, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands., Khyali J; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands., Juffermans NP; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.; Laboratory of Translational Intensive Care, Erasmus MC, University Medical Center, Rotterdam, the Netherlands., Gommers D; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands., van Gorp ECM; Department of Viroscience, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Bos LDJ; Department of Intensive Care, Location Academic Medical Centre, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.; Laboratory of Experimental Intensive Care and Anesthesiology, Location Academic Medical Centre, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands., Endeman H; Department of Intensive Care, Erasmus University Medical Center Rotterdam, Doctor Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands.; Department of Intensive Care, OLVG, Amsterdam, The Netherlands.
Source: Clinical and experimental medicine [Clin Exp Med] 2025 Nov 11; Vol. 25 (1), pp. 361. Date of Electronic Publication: 2025 Nov 11.
Publication Type: Journal Article; Observational Study
Journal Info: Publisher: Springer-Verlag Italia Country of Publication: Italy NLM ID: 100973405 Publication Model: Electronic Cited Medium: Internet ISSN: 1591-9528 (Electronic) Linking ISSN: 15918890 NLM ISO Abbreviation: Clin Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1591-9528
DOI:10.1007/s10238-025-01904-8