13C metabolic tracing in human SGBS cells provides a potential new approach methodology for assessing metabolism-disrupting properties of environmental chemicals.

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Title: 13C metabolic tracing in human SGBS cells provides a potential new approach methodology for assessing metabolism-disrupting properties of environmental chemicals.
Authors: Goerdeler C; Department of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany., Engelmann B; Department of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany., Broghammer H; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz-Centre Munich at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Aldehoff AS; Department of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany., Wabitsch M; Division of Pediatric Endocrinology and Diabetes, Ulm University Medical Center, Ulm, Germany; German Centre for Child and Adolescent Health (DZKJ), Germany., Schubert K; Department of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany., Blüher M; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz-Centre Munich at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany; German Centre for Child and Adolescent Health (DZKJ), Germany; Department of Endocrinology, Nephrology and Rheumatology, University of Leipzig, Leipzig, Germany., Heiker JT; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz-Centre Munich at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany., Rolle-Kampczyk U; Department of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany. Electronic address: ulrike.rolle-kampczyk@ufz.de., von Bergen M; Department of Molecular Toxicology, Helmholtz Centre for Environmental Research (UFZ), Leipzig, Germany; German Centre for Child and Adolescent Health (DZKJ), Germany; Institute of Biochemistry, Leipzig University, Leipzig, Germany; German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Leipzig, Germany.
Source: Journal of hazardous materials [J Hazard Mater] 2025 Dec 05; Vol. 500, pp. 140384. Date of Electronic Publication: 2025 Nov 04.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9422688 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3336 (Electronic) Linking ISSN: 03043894 NLM ISO Abbreviation: J Hazard Mater Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-3336
DOI:10.1016/j.jhazmat.2025.140384