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Single-cell transcriptome profiling of post-treatment and treatment-naïve colorectal cancer: Insights into putative mechanisms of chemoresistance.

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Title: Single-cell transcriptome profiling of post-treatment and treatment-naïve colorectal cancer: Insights into putative mechanisms of chemoresistance.
Authors: Puzanov GA; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France. Electronic address: grigorypuzanov@gmail.com., Astier C; ERC Chromatin Remodeling, DNA Repair and Epigenetics Laboratory, INSERM U981, Gustave Roussy, Villejuif, France; Université Paris-Saclay, Université Paris-Sud XI, Faculté de Médicine, Le Kremlin Bicêtre, France., Papakonstantinou D; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France., Quiroga Londoño M; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France., Blériot C; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France., Yurchenko AA; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France., Bani MA; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France., Jules-Clement G; Gustave Roussy, Université Paris-Saclay, Bioinformatics Core Facility, Inserm US23, CNRS UMS 3655, Villejuif, France., Andre F; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France., Marabelle A; Laboratoire de Recherche Translationnelle en Immunotherapie (LRTI), INSERM U1015, Villejuif, France; Centre d'Investigation Clinique BIOTHERIS, INSERM CIC1428, Villejuif, France; Département d'Innovation Thérapeutique et d'Essais Précoces (DITEP), INSERM U1015, Villejuif, France; Faculté de Médecine, Université Paris Saclay, Le Kremlin Bicêtre, France., Hollebecque A; Gustave Roussy, Department of Medical Oncology, Villejuif, France; Gustave Roussy, Early Drug Development Department (DITEP), Villejuif, France., Nikolaev SI; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France. Electronic address: Sergey.Nikolaev@gustaveroussy.fr.
Source: Cancer letters [Cancer Lett] 2026 Jan 01; Vol. 636, pp. 218127. Date of Electronic Publication: 2025 Nov 09.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ireland Country of Publication: Ireland NLM ID: 7600053 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7980 (Electronic) Linking ISSN: 03043835 NLM ISO Abbreviation: Cancer Lett Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Single-cell transcriptome profiling of post-treatment and treatment-naïve colorectal cancer: Insights into putative mechanisms of chemoresistance.
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  Data: <searchLink fieldCode="AU" term="%22Puzanov+GA%22">Puzanov GA</searchLink>; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France. Electronic address: grigorypuzanov@gmail.com.<br /><searchLink fieldCode="AU" term="%22Astier+C%22">Astier C</searchLink>; ERC Chromatin Remodeling, DNA Repair and Epigenetics Laboratory, INSERM U981, Gustave Roussy, Villejuif, France; Université Paris-Saclay, Université Paris-Sud XI, Faculté de Médicine, Le Kremlin Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Papakonstantinou+D%22">Papakonstantinou D</searchLink>; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Quiroga+Londoño+M%22">Quiroga Londoño M</searchLink>; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Blériot+C%22">Blériot C</searchLink>; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Yurchenko+AA%22">Yurchenko AA</searchLink>; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Bani+MA%22">Bani MA</searchLink>; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Jules-Clement+G%22">Jules-Clement G</searchLink>; Gustave Roussy, Université Paris-Saclay, Bioinformatics Core Facility, Inserm US23, CNRS UMS 3655, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Andre+F%22">Andre F</searchLink>; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Marabelle+A%22">Marabelle A</searchLink>; Laboratoire de Recherche Translationnelle en Immunotherapie (LRTI), INSERM U1015, Villejuif, France; Centre d'Investigation Clinique BIOTHERIS, INSERM CIC1428, Villejuif, France; Département d'Innovation Thérapeutique et d'Essais Précoces (DITEP), INSERM U1015, Villejuif, France; Faculté de Médecine, Université Paris Saclay, Le Kremlin Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Hollebecque+A%22">Hollebecque A</searchLink>; Gustave Roussy, Department of Medical Oncology, Villejuif, France; Gustave Roussy, Early Drug Development Department (DITEP), Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Nikolaev+SI%22">Nikolaev SI</searchLink>; Université Paris-Saclay, Gustave Roussy, Inserm U981, Villejuif, France. Electronic address: Sergey.Nikolaev@gustaveroussy.fr.
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  Data: <searchLink fieldCode="JN" term="%227600053%22">Cancer letters</searchLink> [Cancer Lett] 2026 Jan 01; Vol. 636, pp. 218127. <i>Date of Electronic Publication: </i>2025 Nov 09.
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              Text: 2026 Jan 01
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