YTHDF2 regulates self non-coding RNA metabolism to control inflammation and tumorigenesis.

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Title: YTHDF2 regulates self non-coding RNA metabolism to control inflammation and tumorigenesis.
Authors: Yang S; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA. syang80research@gmail.com., Cui YH; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA., Li H; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA., Wei J; Departments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA., Park G; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA., Sun M; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA., Verghese M; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA., Wilkinson E; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA., Nam T; The College, University of Chicago, Chicago, IL, USA., Lungstrom LL; The College, University of Chicago, Chicago, IL, USA., Cui X; Departments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA., Ryu TY; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA., Chen J; Department of Medicine, Section of Hematology and Oncology, University of Chicago, Chicago, IL, USA., Bissonnette M; Department of Medicine, Section of Gastroenterology, Hepatology & Nutrition, University of Chicago, Chicago, IL, USA., He C; Departments of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, University of Chicago, Chicago, IL, USA., He YY; Department of Medicine, Section of Dermatology, University of Chicago, Chicago, IL, USA. yyhe@uchicago.edu.
Source: Nature communications [Nat Commun] 2025 Nov 12; Vol. 16 (1), pp. 9946. Date of Electronic Publication: 2025 Nov 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-64898-7