Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection.
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| Title: | Non-apoptotic caspase-8 is critical for orchestrating exaggerated inflammation during severe SARS-CoV-2 infection. |
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| Authors: | M Bader S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia. bader.s@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. bader.s@wehi.edu.au., Scherer L; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Bhandari R; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Motyer AJ; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Cooney JP; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Mackiewicz L; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia., Dayton M; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia., Sheerin D; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., V L Romero D; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Schaefer J; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Pang J; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Chen S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; College of Life Sciences, Nankai University, Tianjin, China., Schoffer K; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia., Wang L; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Jin X; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Batey D; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia., Yip RKH; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Zaman I; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia., Rajasekhar P; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Gartner MJ; Department of Microbiology and Immunology, the University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, Australia., Wilcox S; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Whitehead L; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Georgy SR; Section of Anatomic Pathology, Melbourne Veterinary School, Faculty of Science, University of Melbourne, Werribee, Victoria, VIC, Australia., Maluenda A; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia., Davidson KC; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Allison CC; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia., Bowden R; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Brinkmann K; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Asselin-Labat ML; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Phipson B; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Tanzer MC; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Herold MJ; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia.; Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, VIC, Australia.; School of Cancer Medicine, La Trobe University, Heidelberg, Victoria, VIC, Australia., Samson AL; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Vince JE; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Strasser A; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia., Pellegrini M; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia. m.pellegrini@centenary.org.au.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. m.pellegrini@centenary.org.au.; Centenary Institute and University of Technology Sydney, Faculty of Science, School of Life Sciences, Sydney, NSW, Australia. m.pellegrini@centenary.org.au., Doerflinger M; The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, VIC, Australia. doerflinger.m@wehi.edu.au.; Department of Medical Biology, University of Melbourne, Melbourne, VIC, Australia. doerflinger.m@wehi.edu.au. |
| Source: | Nature communications [Nat Commun] 2025 Nov 13; Vol. 16 (1), pp. 9822. Date of Electronic Publication: 2025 Nov 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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