Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding.
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| Title: | Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding. |
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| Authors: | van der Plas-van Duijn A; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands., Winkelman LMT; Division of Cell Systems and Drug Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Lensen C; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands., van Duivendijk M; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands., Derksen I; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands., van Veenendaal JMF; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands., Schaap G; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands., Sluijter M; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands., van Groningen TJB; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands., van Doorn R; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands., van Hall T; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands., Slieker RC; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands., Sharp TH; School of Biochemistry, University of Bristol, Bristol, United Kingdom., Beltman JB; Division of Cell Systems and Drug Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands., Bresser K; T Cell Differentiation Lab, Department of Research, Sanquin Blood Supply Foundation, Amsterdam, the Netherlands., Scheeren FA; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands. f.a.scheeren@lumc.nl. |
| Source: | Communications biology [Commun Biol] 2025 Nov 13; Vol. 8 (1), pp. 1561. Date of Electronic Publication: 2025 Nov 13. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41233527 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22van+der+Plas-van+Duijn+A%22">van der Plas-van Duijn A</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Winkelman+LMT%22">Winkelman LMT</searchLink>; Division of Cell Systems and Drug Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Lensen+C%22">Lensen C</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Duivendijk+M%22">van Duivendijk M</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Derksen+I%22">Derksen I</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Veenendaal+JMF%22">van Veenendaal JMF</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Schaap+G%22">Schaap G</searchLink>; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Sluijter+M%22">Sluijter M</searchLink>; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Groningen+TJB%22">van Groningen TJB</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Doorn+R%22">van Doorn R</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Hall+T%22">van Hall T</searchLink>; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Slieker+RC%22">Slieker RC</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Medical Oncology, Oncode institute, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Sharp+TH%22">Sharp TH</searchLink>; School of Biochemistry, University of Bristol, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Beltman+JB%22">Beltman JB</searchLink>; Division of Cell Systems and Drug Safety, Leiden Academic Centre for Drug Research, Leiden University, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Bresser+K%22">Bresser K</searchLink>; T Cell Differentiation Lab, Department of Research, Sanquin Blood Supply Foundation, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Scheeren+FA%22">Scheeren FA</searchLink>; Department of Dermatology, Leiden University Medical Center, Leiden, the Netherlands. f.a.scheeren@lumc.nl. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101719179%22">Communications biology</searchLink> [Commun Biol] 2025 Nov 13; Vol. 8 (1), pp. 1561. <i>Date of Electronic Publication: </i>2025 Nov 13. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+UK%22">Nature Publishing Group UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101719179 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2399-3642 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223993642%22">23993642 </searchLink><i>NLM ISO Abbreviation: </i>Commun Biol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41233527 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s42003-025-08938-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1561 Titles: – TitleFull: Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: van der Plas-van Duijn A – PersonEntity: Name: NameFull: Winkelman LMT – PersonEntity: Name: NameFull: Lensen C – PersonEntity: Name: NameFull: van Duivendijk M – PersonEntity: Name: NameFull: Derksen I – PersonEntity: Name: NameFull: van Veenendaal JMF – PersonEntity: Name: NameFull: Schaap G – PersonEntity: Name: NameFull: Sluijter M – PersonEntity: Name: NameFull: van Groningen TJB – PersonEntity: Name: NameFull: van Doorn R – PersonEntity: Name: NameFull: van Hall T – PersonEntity: Name: NameFull: Slieker RC – PersonEntity: Name: NameFull: Sharp TH – PersonEntity: Name: NameFull: Beltman JB – PersonEntity: Name: NameFull: Bresser K – PersonEntity: Name: NameFull: Scheeren FA IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 11 Text: 2025 Nov 13 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2399-3642 Numbering: – Type: volume Value: 8 – Type: issue Value: 1 Titles: – TitleFull: Communications biology Type: main |
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