Integrative multi-omic profiling in blood reveals distinct immune and metabolic signatures between ACPA-negative and ACPA-positive rheumatoid arthritis.
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| Title: | Integrative multi-omic profiling in blood reveals distinct immune and metabolic signatures between ACPA-negative and ACPA-positive rheumatoid arthritis. |
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| Authors: | Hur B; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.; Microbiomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, United States., Gupta VK; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.; Microbiomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, United States., Oh M; School of Software Convergence, Myongji University, Seoul, Republic of Korea., Zeng H; Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States.; Department of Immunology, Mayo Clinic, Rochester, MN, United States., Crowson CS; Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States.; Division of Clinical Trials and Biostatistics, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States., Warrington KJ; Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States., Myasoedova E; Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States.; Division of Epidemiology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States., Kronzer VL; Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States., Davis JM 3rd; Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States., Sung J; Division of Computational Biology, Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN, United States.; Microbiomics Program, Center for Individualized Medicine, Mayo Clinic, Rochester, MN, United States.; Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States. |
| Source: | Frontiers in immunology [Front Immunol] 2025 Oct 29; Vol. 16, pp. 1667662. Date of Electronic Publication: 2025 Oct 29 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2025.1667662 |
