24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O'Beirne) activity in severely constipated patients.

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Title: 24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O'Beirne) activity in severely constipated patients.
Authors: Bassotti G; Gastroenterology, Hepatology & Digestive Endoscopy Section, Department of Medicine & Surgery, University of Perugia, Perugia, Italy; Gastroenterology & Hepatology Unit, Perugia General Hospital, Perugia, Italy. Electronic address: gabassot@gmail.com., Antonelli E; Gastroenterology & Hepatology Unit, Perugia General Hospital, Perugia, Italy., Bologna S; Gastroenterology, Hepatology & Digestive Endoscopy Section, Department of Medicine & Surgery, University of Perugia, Perugia, Italy., Chen JH; Division of Gastroenterology, Department of Medicine, Farncombe Digestive Health Research Institute, McMaster University, Hamilton, Canada., Huizinga JD; Division of Gastroenterology, Department of Medicine, Farncombe Digestive Health Research Institute, McMaster University, Hamilton, Canada.
Source: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2026 Jan; Vol. 58 (1), pp. 152-154. Date of Electronic Publication: 2025 Nov 14.
Publication Type: Letter
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100958385 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3562 (Electronic) Linking ISSN: 15908658 NLM ISO Abbreviation: Dig Liver Dis Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
Description
ISSN:1878-3562
DOI:10.1016/j.dld.2025.10.024