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24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O'Beirne) activity in severely constipated patients.

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Title: 24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O'Beirne) activity in severely constipated patients.
Authors: Bassotti G; Gastroenterology, Hepatology & Digestive Endoscopy Section, Department of Medicine & Surgery, University of Perugia, Perugia, Italy; Gastroenterology & Hepatology Unit, Perugia General Hospital, Perugia, Italy. Electronic address: gabassot@gmail.com., Antonelli E; Gastroenterology & Hepatology Unit, Perugia General Hospital, Perugia, Italy., Bologna S; Gastroenterology, Hepatology & Digestive Endoscopy Section, Department of Medicine & Surgery, University of Perugia, Perugia, Italy., Chen JH; Division of Gastroenterology, Department of Medicine, Farncombe Digestive Health Research Institute, McMaster University, Hamilton, Canada., Huizinga JD; Division of Gastroenterology, Department of Medicine, Farncombe Digestive Health Research Institute, McMaster University, Hamilton, Canada.
Source: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver [Dig Liver Dis] 2026 Jan; Vol. 58 (1), pp. 152-154. Date of Electronic Publication: 2025 Nov 14.
Publication Type: Letter
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 100958385 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3562 (Electronic) Linking ISSN: 15908658 NLM ISO Abbreviation: Dig Liver Dis Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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  Data: 24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O'Beirne) activity in severely constipated patients.
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  Data: <searchLink fieldCode="AU" term="%22Bassotti+G%22">Bassotti G</searchLink>; Gastroenterology, Hepatology & Digestive Endoscopy Section, Department of Medicine & Surgery, University of Perugia, Perugia, Italy; Gastroenterology & Hepatology Unit, Perugia General Hospital, Perugia, Italy. Electronic address: gabassot@gmail.com.<br /><searchLink fieldCode="AU" term="%22Antonelli+E%22">Antonelli E</searchLink>; Gastroenterology & Hepatology Unit, Perugia General Hospital, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Bologna+S%22">Bologna S</searchLink>; Gastroenterology, Hepatology & Digestive Endoscopy Section, Department of Medicine & Surgery, University of Perugia, Perugia, Italy.<br /><searchLink fieldCode="AU" term="%22Chen+JH%22">Chen JH</searchLink>; Division of Gastroenterology, Department of Medicine, Farncombe Digestive Health Research Institute, McMaster University, Hamilton, Canada.<br /><searchLink fieldCode="AU" term="%22Huizinga+JD%22">Huizinga JD</searchLink>; Division of Gastroenterology, Department of Medicine, Farncombe Digestive Health Research Institute, McMaster University, Hamilton, Canada.
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  Data: <searchLink fieldCode="JN" term="%22100958385%22">Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver</searchLink> [Dig Liver Dis] 2026 Jan; Vol. 58 (1), pp. 152-154. <i>Date of Electronic Publication: </i>2025 Nov 14.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>100958385 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-3562 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215908658%22">15908658 </searchLink><i>NLM ISO Abbreviation: </i>Dig Liver Dis <i>Subsets: </i>MEDLINE; In Process
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      – Type: doi
        Value: 10.1016/j.dld.2025.10.024
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      – Code: eng
        Text: English
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      – TitleFull: 24-hour colonic manometry can reveal exaggerated rectosigmoid junction (sphincter of O'Beirne) activity in severely constipated patients.
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              Text: 2026 Jan
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            – TitleFull: Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
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