Interest of a sequential multimodal approach for the treatment of newly diagnosed patients with multimetastatic Ewing sarcoma: results of the French prospective CombinaiR3 phase II trial.
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| Title: | Interest of a sequential multimodal approach for the treatment of newly diagnosed patients with multimetastatic Ewing sarcoma: results of the French prospective CombinaiR3 phase II trial. |
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| Authors: | Laurence V; Adolescents and Young Adults Unit, Medical Oncology and SIREDO (Care, Innovation and Research for Children, Adolescents, and Young Adults with Cancer) Departments, Curie Institute, Paris, France., Jehanno N; Department of Nuclear Medicine, Curie Institute, Paris, France., Dureau S; Department of Biometry, Curie Institute, Saint Cloud, France., Mous L; Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland., Claude L; Department of Radiation Oncology, Centre Léon Bérard, Lyon, France., Ballet S; Genetics Department Curie Institute & PSL Research University, Paris, France., Pierron G; Genetics Department Curie Institute & PSL Research University, Paris, France., Gaspar N; Department of Oncology for Children and Adolescents, Gustave Roussy Institute, Villejuif, France., Brahmi M; Department of Medical Oncology, Centre Léon Bérard, Lyon, France., Valentin T; Department of Medical Oncology, Institut Claudius Regaud, Institut Universitaire du Cancer de Toulouse - Oncopole, Toulouse, France., Revon-Rivière G; Department of Pediatric Hematology, Immunology and Oncology, APHM - La Timone Children's Hospital, Marseille, France., Lervat C; Department of Pediatric and AYA Oncology, Centre Oscar Lambret, Lille, France., Probert J; Department of Pediatric Onco-hematology, University Hospital of Rennes, Rennes, France., Entz-Werle N; Department of Pediatric Onco-hematology, University Hospitals of Strasbourg, Strasbourg, France., Mansuy L; Department of Pediatric Hematology and Oncology, Children's University Hospital, Nancy, France., Plantaz D; Department of Pediatric Hematology and Oncology, University Hospital of Grenoble, Grenoble, France., Rios M; Department of Medical Oncology, Institut de Cancérologie de Lorraine-Alexis Vautrin, Vandoeuvre-lès-Nancy, France., Saumet L; Department of Pediatric Onco-Hematology, University Hospital of Montpellier, Montpellier, Languedoc-Roussillon, France., Vérité C; Department of Pediatric and Adolescent Hematology and Oncology, Pellegrin Hospital, Bordeaux, France., Castex MP; Pediatric Oncology Immunology Hematology Unit, Children's University Hospital - Toulouse University Hospital, Toulouse, France., Thebaud E; Department of Pediatric Oncology, Hôpital Mère-Enfant, Nantes, France., Cassou-Mounat T; Nuclear Medicine Department, Institut Claudius Regaud, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France., Plissonnier AS; DREH Pôle Promotion, Institut Curie, Saint-Cloud, France., Dieppedale J; Department of Biometry, Curie Institute, Saint Cloud, France., Delattre O; INSERM U830, Diversity and Plasticity of Childhood Tumors Lab, SIREDO Oncology Center, Curie Institute Research Center, PSL Research University, Paris, France., Legrier ME; DREH Pôle Promotion, Institut Curie, Saint-Cloud, France., Marec-Bérard P; Department of Pediatric Oncology, Institute for Paediatric Haematology and Oncology, Centre Léon Bérard, Lyon, France., Gouin F; Department of Surgical Oncology, Centre Léon Bérard, Lyon, France., Berlanga P; Department of Oncology for Children and Adolescents, Gustave Roussy Institute, Villejuif, France., Cordero C; Adolescents and Young Adults Unit, Medical Oncology and SIREDO (Care, Innovation and Research for Children, Adolescents, and Young Adults with Cancer) Departments, Curie Institute, Paris, France., Surdez D; Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland., Corradini N; Department of Pediatric Oncology, Institute for Paediatric Haematology and Oncology, Centre Léon Bérard, Lyon, France. nadege.corradini@ihope.fr. |
| Source: | British journal of cancer [Br J Cancer] 2026 Jan; Vol. 134 (2), pp. 279-288. Date of Electronic Publication: 2025 Nov 17. |
| Publication Type: | Journal Article; Clinical Trial, Phase II; Multicenter Study |
| Journal Info: | Publisher: Nature Publishing Group on behalf of Cancer Research UK Country of Publication: England NLM ID: 0370635 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-1827 (Electronic) Linking ISSN: 00070920 NLM ISO Abbreviation: Br J Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41249450 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Interest of a sequential multimodal approach for the treatment of newly diagnosed patients with multimetastatic Ewing sarcoma: results of the French prospective CombinaiR3 phase II trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Laurence+V%22">Laurence V</searchLink>; Adolescents and Young Adults Unit, Medical Oncology and SIREDO (Care, Innovation and Research for Children, Adolescents, and Young Adults with Cancer) Departments, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Jehanno+N%22">Jehanno N</searchLink>; Department of Nuclear Medicine, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Dureau+S%22">Dureau S</searchLink>; Department of Biometry, Curie Institute, Saint Cloud, France.<br /><searchLink fieldCode="AU" term="%22Mous+L%22">Mous L</searchLink>; Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Claude+L%22">Claude L</searchLink>; Department of Radiation Oncology, Centre Léon Bérard, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Ballet+S%22">Ballet S</searchLink>; Genetics Department Curie Institute & PSL Research University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Pierron+G%22">Pierron G</searchLink>; Genetics Department Curie Institute & PSL Research University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Gaspar+N%22">Gaspar N</searchLink>; Department of Oncology for Children and Adolescents, Gustave Roussy Institute, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Brahmi+M%22">Brahmi M</searchLink>; Department of Medical Oncology, Centre Léon Bérard, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Valentin+T%22">Valentin T</searchLink>; Department of Medical Oncology, Institut Claudius Regaud, Institut Universitaire du Cancer de Toulouse - Oncopole, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Revon-Rivière+G%22">Revon-Rivière G</searchLink>; Department of Pediatric Hematology, Immunology and Oncology, APHM - La Timone Children's Hospital, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Lervat+C%22">Lervat C</searchLink>; Department of Pediatric and AYA Oncology, Centre Oscar Lambret, Lille, France.<br /><searchLink fieldCode="AU" term="%22Probert+J%22">Probert J</searchLink>; Department of Pediatric Onco-hematology, University Hospital of Rennes, Rennes, France.<br /><searchLink fieldCode="AU" term="%22Entz-Werle+N%22">Entz-Werle N</searchLink>; Department of Pediatric Onco-hematology, University Hospitals of Strasbourg, Strasbourg, France.<br /><searchLink fieldCode="AU" term="%22Mansuy+L%22">Mansuy L</searchLink>; Department of Pediatric Hematology and Oncology, Children's University Hospital, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Plantaz+D%22">Plantaz D</searchLink>; Department of Pediatric Hematology and Oncology, University Hospital of Grenoble, Grenoble, France.<br /><searchLink fieldCode="AU" term="%22Rios+M%22">Rios M</searchLink>; Department of Medical Oncology, Institut de Cancérologie de Lorraine-Alexis Vautrin, Vandoeuvre-lès-Nancy, France.<br /><searchLink fieldCode="AU" term="%22Saumet+L%22">Saumet L</searchLink>; Department of Pediatric Onco-Hematology, University Hospital of Montpellier, Montpellier, Languedoc-Roussillon, France.<br /><searchLink fieldCode="AU" term="%22Vérité+C%22">Vérité C</searchLink>; Department of Pediatric and Adolescent Hematology and Oncology, Pellegrin Hospital, Bordeaux, France.<br /><searchLink fieldCode="AU" term="%22Castex+MP%22">Castex MP</searchLink>; Pediatric Oncology Immunology Hematology Unit, Children's University Hospital - Toulouse University Hospital, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Thebaud+E%22">Thebaud E</searchLink>; Department of Pediatric Oncology, Hôpital Mère-Enfant, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Cassou-Mounat+T%22">Cassou-Mounat T</searchLink>; Nuclear Medicine Department, Institut Claudius Regaud, Institut Universitaire du Cancer Toulouse Oncopole, Toulouse, France.<br /><searchLink fieldCode="AU" term="%22Plissonnier+AS%22">Plissonnier AS</searchLink>; DREH Pôle Promotion, Institut Curie, Saint-Cloud, France.<br /><searchLink fieldCode="AU" term="%22Dieppedale+J%22">Dieppedale J</searchLink>; Department of Biometry, Curie Institute, Saint Cloud, France.<br /><searchLink fieldCode="AU" term="%22Delattre+O%22">Delattre O</searchLink>; INSERM U830, Diversity and Plasticity of Childhood Tumors Lab, SIREDO Oncology Center, Curie Institute Research Center, PSL Research University, Paris, France.<br /><searchLink fieldCode="AU" term="%22Legrier+ME%22">Legrier ME</searchLink>; DREH Pôle Promotion, Institut Curie, Saint-Cloud, France.<br /><searchLink fieldCode="AU" term="%22Marec-Bérard+P%22">Marec-Bérard P</searchLink>; Department of Pediatric Oncology, Institute for Paediatric Haematology and Oncology, Centre Léon Bérard, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Gouin+F%22">Gouin F</searchLink>; Department of Surgical Oncology, Centre Léon Bérard, Lyon, France.<br /><searchLink fieldCode="AU" term="%22Berlanga+P%22">Berlanga P</searchLink>; Department of Oncology for Children and Adolescents, Gustave Roussy Institute, Villejuif, France.<br /><searchLink fieldCode="AU" term="%22Cordero+C%22">Cordero C</searchLink>; Adolescents and Young Adults Unit, Medical Oncology and SIREDO (Care, Innovation and Research for Children, Adolescents, and Young Adults with Cancer) Departments, Curie Institute, Paris, France.<br /><searchLink fieldCode="AU" term="%22Surdez+D%22">Surdez D</searchLink>; Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Corradini+N%22">Corradini N</searchLink>; Department of Pediatric Oncology, Institute for Paediatric Haematology and Oncology, Centre Léon Bérard, Lyon, France. nadege.corradini@ihope.fr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220370635%22">British journal of cancer</searchLink> [Br J Cancer] 2026 Jan; Vol. 134 (2), pp. 279-288. <i>Date of Electronic Publication: </i>2025 Nov 17. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial, Phase II; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group+on+behalf+of+Cancer+Research+UK%22">Nature Publishing Group on behalf of Cancer Research UK </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0370635 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1532-1827 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200070920%22">00070920 </searchLink><i>NLM ISO Abbreviation: </i>Br J Cancer <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41249450 |
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