Single-cell transcriptomics reveal circulating skin-homing CLA+ CTSW+ cytotoxic CD4+ T cells contribute to relapse of psoriasis.
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| Title: | Single-cell transcriptomics reveal circulating skin-homing CLA+ CTSW+ cytotoxic CD4+ T cells contribute to relapse of psoriasis. |
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| Authors: | Chiu HY; Department of Dermatology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.; Department of Medical Research, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.; Department of Dermatology, National Taiwan University Hospital, Taipei, Taiwan.; Department of Dermatology, College of Medicine, National Taiwan University, Taipei, Taiwan., Chan KK; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu, Taiwan., Wang JR; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.; Institute of Bioinformatics and Systems Biology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu, Taiwan., Liao HT; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Huang HN; Department of Pathology, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.; Department of Pathology and Graduate Institute of Pathology, College of Medicine, National Taiwan University, Taipei, Taiwan., Ko TM; Department of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.; Institute of Bioinformatics and Systems Biology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, Hsinchu, Taiwan.; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; Center for Intelligent Drug Systems and Smart Bio-devices (IDS2B), National Yang Ming Chiao Tung University, Hsinchu, Taiwan.; School of Pharmacy, College of Pharmacy, Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung, Taiwan. |
| Source: | Clinical and translational medicine [Clin Transl Med] 2025 Nov; Vol. 15 (11), pp. e70518. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101597971 Publication Model: Print Cited Medium: Internet ISSN: 2001-1326 (Electronic) Linking ISSN: 20011326 NLM ISO Abbreviation: Clin Transl Med Subsets: MEDLINE; In Process |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2001-1326 |
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| DOI: | 10.1002/ctm2.70518 |
