Placenta-derived trophoblast extracellular vesicles promote CD169+ macrophage migration and suppress ovarian tumour growth.

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Title: Placenta-derived trophoblast extracellular vesicles promote CD169+ macrophage migration and suppress ovarian tumour growth.
Authors: Sun X; Department of Obstetrics, Gynaecology and Reproductive Sciences, Faculty of Medical and Health Science, The University of Auckland, Auckland, New Zealand., Chamley LW; Department of Obstetrics, Gynaecology and Reproductive Sciences, Faculty of Medical and Health Science, The University of Auckland, Auckland, New Zealand., Morgan T; Department of Pathology and Laboratory Medicine, School of Medicine, Oregon Health & Science University, Portland, Maine, USA., Tijono S; Auckland Cancer Society Research Centre, The University of Auckland, Auckland, New Zealand., Tsai B; Department of Obstetrics, Gynaecology and Reproductive Sciences, Faculty of Medical and Health Science, The University of Auckland, Auckland, New Zealand., Terblanche L; Department of Obstetrics, Gynaecology and Reproductive Sciences, Faculty of Medical and Health Science, The University of Auckland, Auckland, New Zealand., Ching LM; Auckland Cancer Society Research Centre, The University of Auckland, Auckland, New Zealand., Chen Q; Department of Obstetrics, Gynaecology and Reproductive Sciences, Faculty of Medical and Health Science, The University of Auckland, Auckland, New Zealand. q.chen@auckland.ac.nz.
Source: Journal of translational medicine [J Transl Med] 2025 Nov 17; Vol. 23 (1), pp. 1295. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1479-5876
DOI:10.1186/s12967-025-07320-6