Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci.

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Title: Combining functional annotation and multi-trait fine-mapping methods improves fine-mapping resolution at glycaemic trait loci.
Authors: Soenksen J; Exeter Centre of Excellence for Diabetes Research (EXCEED), Department of Clinical and Biomedical Sciences, University of Exeter Medical School, University of Exeter, RD&E Hospital Wonford - Barrack Road, Exeter EX2 5DW, United Kingdom.; Living Systems Institute, Department of Clinical and Biomedical Sciences, University of Exeter, Stocker Road, Exeter EX4 4QD, United Kingdom., Chen J; Exeter Centre of Excellence for Diabetes Research (EXCEED), Department of Clinical and Biomedical Sciences, University of Exeter Medical School, University of Exeter, RD&E Hospital Wonford - Barrack Road, Exeter EX2 5DW, United Kingdom., Varshney A; Department of Computational Medicine and Bioinformatics, Palmer Commons, 100 Washtenaw Ave #2017,University of Michigan, Ann Arbor, MI, United States., Martin S; Exeter Centre of Excellence for Diabetes Research (EXCEED), Department of Clinical and Biomedical Sciences, University of Exeter Medical School, University of Exeter, RD&E Hospital Wonford - Barrack Road, Exeter EX2 5DW, United Kingdom., Parker SCJ; Department of Computational Medicine and Bioinformatics, Palmer Commons, 100 Washtenaw Ave #2017,University of Michigan, Ann Arbor, MI, United States.; Department of Human Genetics at the University of Michigan Medical School, 4909 Buhl Building, 1241 Catherine St, University of Michigan, Ann Arbor, MI 48109-2218, United States.; Department of Biostatistics, 1415 Washington Heights, University of Michigan, Ann Arbor, MI 48109-2029, United States., Morris AP; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, University of Manchester, 2nd floor, Stopford Building, Oxford Road, Manchester M13 9PT, United Kingdom., Asimit JL; MRC Biostatistics Unit, Institute of Public Health, University of Cambridge, School of Clinical Medicine, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge CB2 0SR, United Kingdom., Barroso I; Exeter Centre of Excellence for Diabetes Research (EXCEED), Department of Clinical and Biomedical Sciences, University of Exeter Medical School, University of Exeter, RD&E Hospital Wonford - Barrack Road, Exeter EX2 5DW, United Kingdom.
Source: Human molecular genetics [Hum Mol Genet] 2026 Feb 09; Vol. 35 (2).
Publication Type: Journal Article
Journal Info: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1460-2083
DOI:10.1093/hmg/ddaf164