EVOLVE platform, a trispecific T cell engager with integrated CD2 costimulation, for the treatment of solid and hematologic tumors.

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Title: EVOLVE platform, a trispecific T cell engager with integrated CD2 costimulation, for the treatment of solid and hematologic tumors.
Authors: Sergeeva OA; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Jin G; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Sarkar M; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Zeiger J; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Dhindwal S; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Chin SS; EvolveImmune Therapeutics, Inc., Branford, CT 06405.; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591., Abulizi A; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Lai Z; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Brown C; EvolveImmune Therapeutics, Inc., Branford, CT 06405., DeMaria WG; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Ryan D; EvolveImmune Therapeutics, Inc., Branford, CT 06405., An X; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Karp HJ; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Teran E; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Yuan C; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Klaskin D; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Reeve TA; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Yu GK; Independent Consultant, Kensington, CA 94708., Tam EM; EvolveImmune Therapeutics, Inc., Branford, CT 06405.; Antibody Technology Fred Hutchinson Cancer Center, Seattle, WA 98109., Kaech SM; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA 92037., Preyer M; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Matis L; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Fine JS; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Martomo SA; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Myers JS; EvolveImmune Therapeutics, Inc., Branford, CT 06405.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 25; Vol. 122 (47), pp. e2510829122. Date of Electronic Publication: 2025 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2510829122