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EVOLVE platform, a trispecific T cell engager with integrated CD2 costimulation, for the treatment of solid and hematologic tumors.

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Title: EVOLVE platform, a trispecific T cell engager with integrated CD2 costimulation, for the treatment of solid and hematologic tumors.
Authors: Sergeeva OA; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Jin G; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Sarkar M; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Zeiger J; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Dhindwal S; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Chin SS; EvolveImmune Therapeutics, Inc., Branford, CT 06405.; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591., Abulizi A; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Lai Z; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Brown C; EvolveImmune Therapeutics, Inc., Branford, CT 06405., DeMaria WG; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Ryan D; EvolveImmune Therapeutics, Inc., Branford, CT 06405., An X; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Karp HJ; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Teran E; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Yuan C; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Klaskin D; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Reeve TA; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Yu GK; Independent Consultant, Kensington, CA 94708., Tam EM; EvolveImmune Therapeutics, Inc., Branford, CT 06405.; Antibody Technology Fred Hutchinson Cancer Center, Seattle, WA 98109., Kaech SM; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA 92037., Preyer M; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Matis L; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Fine JS; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Martomo SA; EvolveImmune Therapeutics, Inc., Branford, CT 06405., Myers JS; EvolveImmune Therapeutics, Inc., Branford, CT 06405.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2025 Nov 25; Vol. 122 (47), pp. e2510829122. Date of Electronic Publication: 2025 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: EVOLVE platform, a trispecific T cell engager with integrated CD2 costimulation, for the treatment of solid and hematologic tumors.
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  Data: <searchLink fieldCode="AU" term="%22Sergeeva+OA%22">Sergeeva OA</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Jin+G%22">Jin G</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Sarkar+M%22">Sarkar M</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Zeiger+J%22">Zeiger J</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Dhindwal+S%22">Dhindwal S</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Chin+SS%22">Chin SS</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591.<br /><searchLink fieldCode="AU" term="%22Abulizi+A%22">Abulizi A</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Lai+Z%22">Lai Z</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Brown+C%22">Brown C</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22DeMaria+WG%22">DeMaria WG</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Ryan+D%22">Ryan D</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22An+X%22">An X</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Karp+HJ%22">Karp HJ</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Teran+E%22">Teran E</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Yuan+C%22">Yuan C</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Klaskin+D%22">Klaskin D</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Reeve+TA%22">Reeve TA</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Yu+GK%22">Yu GK</searchLink>; Independent Consultant, Kensington, CA 94708.<br /><searchLink fieldCode="AU" term="%22Tam+EM%22">Tam EM</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.; Antibody Technology Fred Hutchinson Cancer Center, Seattle, WA 98109.<br /><searchLink fieldCode="AU" term="%22Kaech+SM%22">Kaech SM</searchLink>; NOMIS Center for Immunobiology and Microbial Pathogenesis, Salk Institute for Biological Studies, La Jolla, CA 92037.<br /><searchLink fieldCode="AU" term="%22Preyer+M%22">Preyer M</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Matis+L%22">Matis L</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Fine+JS%22">Fine JS</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Martomo+SA%22">Martomo SA</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.<br /><searchLink fieldCode="AU" term="%22Myers+JS%22">Myers JS</searchLink>; EvolveImmune Therapeutics, Inc., Branford, CT 06405.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2025 Nov 25; Vol. 122 (47), pp. e2510829122. <i>Date of Electronic Publication: </i>2025 Nov 18.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22National+Academy+of+Sciences%22">National Academy of Sciences </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7505876 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1091-6490 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200278424%22">00278424 </searchLink><i>NLM ISO Abbreviation: </i>Proc Natl Acad Sci U S A <i>Subsets: </i>MEDLINE
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