LRRK2 p.G2385R and p.R1628P variants in a multi-ethnic Asian Parkinson's Cohort: epidemiology and clinical insights.
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| Title: | LRRK2 p.G2385R and p.R1628P variants in a multi-ethnic Asian Parkinson's Cohort: epidemiology and clinical insights. |
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| Authors: | Goh JW; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Lim JL; Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Toh TS; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Ong RY; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Yong QH; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Lew CCY; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Hor JW; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Tay YW; Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Zulkefli J; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.; Immunogenetic Unit, Allergy and Immunology Research Centre, Institute for Medical Research, National Institutes of Health Complex, Ministry of Health Malaysia, Setia Alam, Malaysia., Khairul Anuar AN; Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Ding HX; Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Schee JP; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Beh YY; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Ibrahim KA; Department of Medicine, Hospital Sultanah Nur Zahirah, Terengganu, Malaysia., Mawardi AS; Department of Neurology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia., Lim TT; Island Hospital, Penang, Malaysia., Looi I; Department of Neurology, Seberang Jaya Hospital, Penang, Malaysia., Chia YK; Department of Neurology, Queen Elizabeth Hospital, Sabah, Malaysia., Ooi JCE; Department of Neurology, Queen Elizabeth Hospital, Sabah, Malaysia., Law WC; Department of Neurology, Hospital Umum Sarawak, Sarawak, Malaysia., Wong SC; Department of Neurology, Hospital Umum Sarawak, Sarawak, Malaysia., Lau YH; Department of Medicine, Hospital Tengku Ampuan Rahimah, Selangor, Malaysia., Teh PC; Department of Medicine, Hospital Tuanku Jaafar, Negeri Sembilan, Malaysia., Ong TL; Department of Medicine, Hospital Sungai Buloh, Selangor, Malaysia., Cheah WK; Department of Medicine, Hospital Taiping, Perak, Malaysia., Sammler E; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee, UK.; Division of Neuroscience, School of Medicine, University of Dundee, Dundee, UK., Padmanabhan S; The Michael J. Fox Foundation for Parkinson's Research, New York, NY, USA., Lit LC; Department of Physiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia., Tan EK; Department of Neurology, National Neuroscience Institute, Singapore, Singapore., Ahmad-Annuar A; Department of Biomedical Science, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. azlina_aa@um.edu.my., Lim SY; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. limshenyang@gmail.com., Tan AH; Division of Neurology, Department of Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. aihuey.tan@gmail.com. |
| Source: | NPJ Parkinson's disease [NPJ Parkinsons Dis] 2025 Nov 18; Vol. 11 (1), pp. 320. Date of Electronic Publication: 2025 Nov 18. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2373-8057 |
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| DOI: | 10.1038/s41531-025-01166-x |
