Extracellular matrix stiffness modulates angiogenic properties of the retinal pigment epithelium.

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Title: Extracellular matrix stiffness modulates angiogenic properties of the retinal pigment epithelium.
Authors: Wolfram L; Eye Center, Medical Center - Faculty of Medicine, University of Freiburg, Freiburg, Germany. lasse.wolfram@med.uni-tuebingen.de.; Department for Ophthalmology, Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Germany. lasse.wolfram@med.uni-tuebingen.de.; Department for Ophthalmology, University Eye Clinic, Eberhard Karls University of Tübingen, Tübingen, Germany. lasse.wolfram@med.uni-tuebingen.de., Schwämmle M; Eye Center, Medical Center - Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Gimpel C; Eye Center, Medical Center - Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Department of Neurology, Schlosspark-Klinik Charlottenburg, Berlin, Germany., Merle DA; Department for Ophthalmology, Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Germany.; Department for Ophthalmology, University Eye Clinic, Eberhard Karls University of Tübingen, Tübingen, Germany., Tang J; Department for Ophthalmology, Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Germany., Clark SJ; Department for Ophthalmology, Institute for Ophthalmic Research, Eberhard Karls University of Tübingen, Tübingen, Germany.; Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK., Böhringer D; Eye Center, Medical Center - Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schlunck G; Eye Center, Medical Center - Faculty of Medicine, University of Freiburg, Freiburg, Germany. guenther.schlunck@uniklinik-freiburg.de.
Source: Scientific reports [Sci Rep] 2025 Nov 18; Vol. 15 (1), pp. 40349. Date of Electronic Publication: 2025 Nov 18.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2045-2322
DOI:10.1038/s41598-025-27140-4