Mechanistic toxicity profiling of nicotine-rich e-liquids: mitochondrial and oxidative stress responses in ALI-exposed bronchial cells.

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Title: Mechanistic toxicity profiling of nicotine-rich e-liquids: mitochondrial and oxidative stress responses in ALI-exposed bronchial cells.
Authors: Emma R; Department of Medicine and Surgery, 'Kore' University of Enna, Contrada Santa Panasia, 94100, Enna, Italy., Distefano A; Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy., Zuccarello P; Department of Psychology and Health Sciences, Pegaso Telematic University, 80143, Naples, Italy., Copat C; Department of Medical, Surgical Sciences and Advanced Technologies 'G.F. Ingrassia', University of Catania, Via S. Sofia, 87, 95123, Catania, Italy., Ferrante M; Department of Medical, Surgical Sciences and Advanced Technologies 'G.F. Ingrassia', University of Catania, Via S. Sofia, 87, 95123, Catania, Italy.; Center of Excellence for the Acceleration of Harm Reduction, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy., Oliveri Conti GM; Department of Medical, Surgical Sciences and Advanced Technologies 'G.F. Ingrassia', University of Catania, Via S. Sofia, 87, 95123, Catania, Italy.; Center of Excellence for the Acceleration of Harm Reduction, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy., Pulvirenti R; Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy., Carota G; Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy. giuseppe-carota@outlook.it.; ECLAT Srl, University of Catania, Via S. Sofia, 89, 95123, Catania, Italy. giuseppe-carota@outlook.it., Campagna D; Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy., Polosa R; Center of Excellence for the Acceleration of Harm Reduction, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy.; Department of Clinical and Experimental Medicine, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy.; ECLAT Srl, University of Catania, Via S. Sofia, 89, 95123, Catania, Italy., Rust S; ECLAT Srl, University of Catania, Via S. Sofia, 89, 95123, Catania, Italy., Caruso M; Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy. mascaru@unict.it.; Center of Excellence for the Acceleration of Harm Reduction, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy. mascaru@unict.it., Li Volti G; Department of Biomedical and Biotechnological Sciences, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy.; Center of Excellence for the Acceleration of Harm Reduction, University of Catania, Via S. Sofia, 97, 95123, Catania, Italy.
Source: Molecular and cellular biochemistry [Mol Cell Biochem] 2026 Feb; Vol. 481 (2), pp. 899-910. Date of Electronic Publication: 2025 Nov 19.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: Netherlands NLM ID: 0364456 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-4919 (Electronic) Linking ISSN: 03008177 NLM ISO Abbreviation: Mol Cell Biochem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1573-4919
DOI:10.1007/s11010-025-05430-9