Random forest model improves annotation and discovery of variants of uncertain significance in Alzheimer's and other neurological disorders.
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| Title: | Random forest model improves annotation and discovery of variants of uncertain significance in Alzheimer's and other neurological disorders. |
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| Authors: | Jonson C; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Makarious MB; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037., Koretsky MJ; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037., Vitale D; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037., Rabkina L; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Lago AL; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA., Eslami-Amirabadi M; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.; University of Washington, School of Medicine, Memory and Brain Wellness Center at Harborview, Seattle, WA, 98104., Ramos EM; Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Narayan P; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892., Yokoyama JS; Memory and Aging Center, Department of Neurology, Weill Institute for Neurosciences, University of California, San Francisco, CA, USA.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA., Singleton AB; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892., Blauwendraat C; Coalition for Aligning Science, Chevy Chase, MD, USA; Global Parkinson's Genetics Program, Chevy Chase, MD, USA; Aligning Science Across Parkinson's (ASAP), Chevy Chase, MD, USA., Cookson MR; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892., Nalls MA; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892., Leonard HL; Center for Alzheimer's and Related Dementias, Bethesda, MD, USA 20892.; DataTecnica LLC, Washington, DC, USA 20037.; Laboratory of Neurogenetics, NIA, NIH, Bethesda, MD, USA 20892. |
| Source: | BioRxiv : the preprint server for biology [bioRxiv] 2025 Oct 02. Date of Electronic Publication: 2025 Oct 02. |
| Publication Type: | Journal Article; Preprint |
| Journal Info: | Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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