Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: Insights into organ toxicities.

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Title: Transcriptional changes in non-human primate tissues after intrathecal delivery of serotype 9 adeno-associated viral vector: Insights into organ toxicities.
Authors: Aihara F; Novartis Biomedical Research, Cambridge, MA, USA., Mardo M; Novartis Biomedical Research, Cambridge, MA, USA., Ruda V; Novartis Biomedical Research, Cambridge, MA, USA., Rio TD; Novartis Biomedical Research, San Diego, CA, USA., Bigot K; Novartis Biomedical Research, Basel, Switzerland., Singer J; Novartis Biomedical Research, Basel, Switzerland., Onishi-Seebacher M; Novartis Biomedical Research, Basel, Switzerland., Couttet P; Novartis Biomedical Research, Basel, Switzerland., Mansfield K; Novartis Biomedical Research, Cambridge, MA, USA., Hudry E; Novartis Biomedical Research, Cambridge, MA, USA.
Source: Molecular therapy. Methods & clinical development [Mol Ther Methods Clin Dev] 2025 Oct 16; Vol. 33 (4), pp. 101617. Date of Electronic Publication: 2025 Oct 16 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101624857 Publication Model: eCollection Cited Medium: Print ISSN: 2329-0501 (Print) Linking ISSN: 23290501 NLM ISO Abbreviation: Mol Ther Methods Clin Dev Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2329-0501
DOI:10.1016/j.omtm.2025.101617