Differential ion selectivity and disease-associated dysfunction of TRPML channels revealed by patient and engineered mutants.

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Bibliographic Details
Title: Differential ion selectivity and disease-associated dysfunction of TRPML channels revealed by patient and engineered mutants.
Authors: Rue BE; Department of Biological Sciences, University of Denver, Denver, Colorado, USA., Dischler AM; Department of Biological Sciences, University of Denver, Denver, Colorado, USA., Salvagio LA; Department of Biological Sciences, University of Denver, Denver, Colorado, USA., Zhu M; Cherry Creek High School, Greenwood Village, Colorado, USA., Xu G; Cherry Creek High School, Greenwood Village, Colorado, USA., Flores PC; Department of Biological Sciences, University of Denver, Denver, Colorado, USA., Donovan CL; Department of Biological Sciences, University of Denver, Denver, Colorado, USA., Liu X; Department of Biological Sciences, University of Denver, Denver, Colorado, USA., Minckley TF; Department of Biological Sciences, University of Denver, Denver, Colorado, USA., Agulnek B; Department of Biological Sciences, University of Denver, Denver, Colorado, USA., Qin Y; Department of Biological Sciences, University of Denver, Denver, Colorado, USA. Electronic address: Yan.Qin@du.edu.
Source: The Journal of biological chemistry [J Biol Chem] 2026 Jan; Vol. 302 (1), pp. 110953. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1083-351X
DOI:10.1016/j.jbc.2025.110953