Single cell long read whole genome sequencing reveals somatic transposon activity in human brain.
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| Title: | Single cell long read whole genome sequencing reveals somatic transposon activity in human brain. |
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| Authors: | Izydorczyk MB; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Kalef-Ezra E; Department of Clinical and Movement Neurosciences, Royal Free Campus, Queen Square Institute of Neurology, University College London, London, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Horner DW; Department of Clinical and Movement Neurosciences, Royal Free Campus, Queen Square Institute of Neurology, University College London, London, UK.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Zheng X; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Holmes N; DeepSeq, School of Life Sciences, University of Nottingham, Nottingham, UK., Toffoli M; Department of Clinical and Movement Neurosciences, Royal Free Campus, Queen Square Institute of Neurology, University College London, London, UK., Sahin Z; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Han Y; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Mehta HH; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Scholz SW; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD, USA.; Department of Neurology, Johns Hopkins University Medical Center, Baltimore, MD, USA., Dalgard CL; Department of Anatomy, Physiology & Genetics, Uniformed Services, University of the Health Sciences (USUHS), Bethesda, MD, USA.; The American Genome Center, USUHS, Bethesda, MD, USA., Muzny DM; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Ameur A; Science for Life Laboratory, Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Sedlazeck FJ; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA. fritz.sedlazeck@bcm.edu.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA. fritz.sedlazeck@bcm.edu.; Department of Computer Science, Rice University, Houston, TX, USA. fritz.sedlazeck@bcm.edu., Proukakis C; Department of Clinical and Movement Neurosciences, Royal Free Campus, Queen Square Institute of Neurology, University College London, London, UK. c.proukakis@ucl.ac.uk.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA. c.proukakis@ucl.ac.uk. |
| Source: | Communications biology [Commun Biol] 2025 Nov 20; Vol. 8 (1), pp. 1627. Date of Electronic Publication: 2025 Nov 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2399-3642 |
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| DOI: | 10.1038/s42003-025-08805-2 |