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Phase I trial to evaluate safety of Deferiprone-Chitogel to prevent epidural fibrosis in lumbar spine surgery.

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Title: Phase I trial to evaluate safety of Deferiprone-Chitogel to prevent epidural fibrosis in lumbar spine surgery.
Authors: Candy NG; Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide, Adelaide, Australia. Nicholas.candy@adelaide.edu.au., Barry EF; Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide, Adelaide, Australia., Tomatis VM; Department of Neurosurgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia., Patel S; Department of Radiology, Jones and Partners, Calvary, Adelaide, Australia.; Department of Radiology, Royal Adelaide Hospital, Adelaide, Australia., Miller J; Department of Neurosurgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia., Ovenden C; Department of Neurosurgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia., Nowicki J; Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia., Hammam E; Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia., Poonnoose S; Department of Neurosurgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia.; College of Medicine and Public Health, Flinders University, Adelaide, Australia., Sandler S; Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia., Wells A; Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia., Vreugde S; Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide, Adelaide, Australia., Wormald PJ; Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide, Adelaide, Australia.
Source: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society [Eur Spine J] 2026 May; Vol. 35 (5), pp. 2778-2787. Date of Electronic Publication: 2025 Nov 22.
Publication Type: Journal Article; Clinical Trial, Phase I
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 9301980 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0932 (Electronic) Linking ISSN: 09406719 NLM ISO Abbreviation: Eur Spine J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase I trial to evaluate safety of Deferiprone-Chitogel to prevent epidural fibrosis in lumbar spine surgery.
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  Data: <searchLink fieldCode="AU" term="%22Candy+NG%22">Candy NG</searchLink>; Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide, Adelaide, Australia. Nicholas.candy@adelaide.edu.au.<br /><searchLink fieldCode="AU" term="%22Barry+EF%22">Barry EF</searchLink>; Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Tomatis+VM%22">Tomatis VM</searchLink>; Department of Neurosurgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Patel+S%22">Patel S</searchLink>; Department of Radiology, Jones and Partners, Calvary, Adelaide, Australia.; Department of Radiology, Royal Adelaide Hospital, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Miller+J%22">Miller J</searchLink>; Department of Neurosurgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Ovenden+C%22">Ovenden C</searchLink>; Department of Neurosurgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Nowicki+J%22">Nowicki J</searchLink>; Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Hammam+E%22">Hammam E</searchLink>; Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Poonnoose+S%22">Poonnoose S</searchLink>; Department of Neurosurgery, Flinders Medical Centre, Bedford Park, Adelaide, Australia.; College of Medicine and Public Health, Flinders University, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Sandler+S%22">Sandler S</searchLink>; Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Wells+A%22">Wells A</searchLink>; Department of Neurosurgery, Royal Adelaide Hospital, Adelaide, Australia.; Faculty of Health and Medical Sciences, University of Adelaide, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Vreugde+S%22">Vreugde S</searchLink>; Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide, Adelaide, Australia.<br /><searchLink fieldCode="AU" term="%22Wormald+PJ%22">Wormald PJ</searchLink>; Department of Surgery - Otolaryngology Head and Neck Surgery, University of Adelaide, Adelaide, Australia.
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  Data: <searchLink fieldCode="JN" term="%229301980%22">European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society</searchLink> [Eur Spine J] 2026 May; Vol. 35 (5), pp. 2778-2787. <i>Date of Electronic Publication: </i>2025 Nov 22.
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              Text: 2026 May
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