A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes.

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Title: A genome-wide CRISPR screen in Anopheles mosquito cells identifies fitness and immune cell function-related genes.
Authors: Mameli E; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Samantsidis GR; Department of Plant Pathology, Entomology and Microbiology, Iowa State University, Ames, IA, USA., Viswanatha R; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Kwon H; Department of Plant Pathology, Entomology and Microbiology, Iowa State University, Ames, IA, USA., Hall DR; Department of Plant Pathology, Entomology and Microbiology, Iowa State University, Ames, IA, USA., Butnaru M; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Hu Y; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Mohr SE; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Perrimon N; Department of Genetics, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. perrimon@genetics.med.harvard.edu.; HHMI, Harvard Medical School, Boston, MA, USA. perrimon@genetics.med.harvard.edu., Smith RC; Department of Plant Pathology, Entomology and Microbiology, Iowa State University, Ames, IA, USA. smithr@iastate.edu.
Source: Nature communications [Nat Commun] 2025 Nov 24; Vol. 16 (1), pp. 10323. Date of Electronic Publication: 2025 Nov 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-65304-y