Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels.
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| Title: | Live-cell quantitative monitoring reveals distinct, high-affinity Gβγ regulations of GIRK2 and GIRK1/2 channels. |
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| Authors: | Handklo-Jamal R; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel., Raifman TK; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel., Shalomov B; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel., Hofer P; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Josef-Holaubek-Platz 2, Vienna, Austria., Kahanovitch U; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel., Friesacher T; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Josef-Holaubek-Platz 2, Vienna, Austria., Tabak G; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel., Tsemakhovich V; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel., Reddy HP; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Neuroscience, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark., Chomsky-Hecht O; Department of Biochemistry & Molecular Biology, School of Neurobiology, Biochemistry and Biophysics, George S. Weiss Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel., Tripathy DR; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Biochemistry & Molecular Biology, School of Neurobiology, Biochemistry and Biophysics, George S. Weiss Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel., Zuhlke K; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany., Dessauer CW; Department of Integrative Biology and Pharmacology, University of Texas Health Science, Center, Houston, Texas, USA., Klussmann E; Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Berlin, Berlin, Germany., Haitin Y; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel., Hirsch JA; Department of Biochemistry & Molecular Biology, School of Neurobiology, Biochemistry and Biophysics, George S. Weiss Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel., Stary-Weinzinger A; Department of Pharmaceutical Sciences, Division of Pharmacology and Toxicology, University of Vienna, Josef-Holaubek-Platz 2, Vienna, Austria. anna.stary@univie.ac.at., Yakubovich D; The Adelson School of Medicine, Ariel University, Ariel, Israel. danielya@ariel.ac.il., Dascal N; Department of Physiology and Pharmacology, Faculty of Health and Medical Sciences, Tel Aviv University, Tel Aviv, Israel. dascaln@tauex.tau.ac.il.; Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel. dascaln@tauex.tau.ac.il. |
| Source: | Nature communications [Nat Commun] 2025 Nov 24; Vol. 16 (1), pp. 11607. Date of Electronic Publication: 2025 Nov 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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