MLM3 and MLM5 head and neck cancer models promote age-dependent musculoskeletal deterioration in mice.
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| Title: | MLM3 and MLM5 head and neck cancer models promote age-dependent musculoskeletal deterioration in mice. |
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| Authors: | Jones AJ; Department of Otolaryngology - Head & Neck Surgery, Cleveland Clinic Foundation, Cleveland, OH, USA., Esteca MV; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, 635 Barnhill Drive. Van Nusy, MS-308, Indianapolis, IN, 46202, USA.; Department of Biochemistry, Federal University of São Paulo, São Paulo, Brazil., Huot JR; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, 635 Barnhill Drive. Van Nusy, MS-308, Indianapolis, IN, 46202, USA.; Indianapolis School of Health and Human Sciences, Department of Kinesiology, Indiana University Purdue University, Indianapolis, IN, USA.; Bren Simon Comprehensive Cancer Center, Indiana University, Indianapolis, IN, USA.; Indiana Center for Musculoskeletal Health, School of Medicine, Indiana University, Indianapolis, IN, USA., Simabuco FM; Department of Biochemistry, Federal University of São Paulo, São Paulo, Brazil., Moore MG; Department of Otolaryngology - Head & Neck Surgery, Indiana University School of Medicine, Indianapolis, IN, USA., Pin F; Department of Anatomy, Cell Biology and Physiology, Indiana University School of Medicine, 635 Barnhill Drive. Van Nusy, MS-308, Indianapolis, IN, 46202, USA. fpin@iu.edu.; Bren Simon Comprehensive Cancer Center, Indiana University, Indianapolis, IN, USA. fpin@iu.edu.; Indiana Center for Musculoskeletal Health, School of Medicine, Indiana University, Indianapolis, IN, USA. fpin@iu.edu. |
| Source: | Scientific reports [Sci Rep] 2025 Nov 24; Vol. 15 (1), pp. 41639. Date of Electronic Publication: 2025 Nov 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2045-2322 |
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| DOI: | 10.1038/s41598-025-25601-4 |