Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs.

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Title: Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs.
Authors: Glauninger H; Graduate Program in Biophysical Sciences, The University of Chicago, Chicago, IL, USA; Interdisciplinary Scientist Training Program, The University of Chicago, Chicago, IL, USA., Bard JAM; Department of Biology, Texas A&M University, College Station, TX, USA., Wong Hickernell CJ; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA., Velez KM; Department of Molecular Genetics & Cell Biology, The University of Chicago, Chicago, IL, USA., Airoldi EM; Fox School of Business and Management, Temple University, Philadelphia, PA, USA., Li W; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY, USA., Singer RH; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY, USA; Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA; Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, NY, USA., Paul S; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA., Fei J; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA., Sosnick TR; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA., Wallace EWJ; School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK. Electronic address: edward.wallace@ed.ac.uk., Drummond DA; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA; Department of Medicine, Section of Genetic Medicine, The University of Chicago, Chicago, IL, USA. Electronic address: dadrummond@uchicago.edu.
Source: Molecular cell [Mol Cell] 2025 Dec 04; Vol. 85 (23), pp. 4393-4409.e11. Date of Electronic Publication: 2025 Nov 24.
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE
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  Data: Transcriptome-wide mRNP condensation precedes stress granule formation and excludes new mRNAs.
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  Data: <searchLink fieldCode="AU" term="%22Glauninger+H%22">Glauninger H</searchLink>; Graduate Program in Biophysical Sciences, The University of Chicago, Chicago, IL, USA; Interdisciplinary Scientist Training Program, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bard+JAM%22">Bard JAM</searchLink>; Department of Biology, Texas A&M University, College Station, TX, USA.<br /><searchLink fieldCode="AU" term="%22Wong+Hickernell+CJ%22">Wong Hickernell CJ</searchLink>; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Velez+KM%22">Velez KM</searchLink>; Department of Molecular Genetics & Cell Biology, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Airoldi+EM%22">Airoldi EM</searchLink>; Fox School of Business and Management, Temple University, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Singer+RH%22">Singer RH</searchLink>; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, New York, NY, USA; Gruss-Lipper Biophotonics Center, Albert Einstein College of Medicine, Bronx, New York, NY, USA; Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Paul+S%22">Paul S</searchLink>; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Fei+J%22">Fei J</searchLink>; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Sosnick+TR%22">Sosnick TR</searchLink>; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA; Pritzker School of Molecular Engineering, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Wallace+EWJ%22">Wallace EWJ</searchLink>; School of Biological Sciences, University of Edinburgh, Edinburgh, Scotland, UK. Electronic address: edward.wallace@ed.ac.uk.<br /><searchLink fieldCode="AU" term="%22Drummond+DA%22">Drummond DA</searchLink>; Department of Biochemistry & Molecular Biology, The University of Chicago, Chicago, IL, USA; Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, USA; Department of Medicine, Section of Genetic Medicine, The University of Chicago, Chicago, IL, USA. Electronic address: dadrummond@uchicago.edu.
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  Data: <searchLink fieldCode="JN" term="%229802571%22">Molecular cell</searchLink> [Mol Cell] 2025 Dec 04; Vol. 85 (23), pp. 4393-4409.e11. <i>Date of Electronic Publication: </i>2025 Nov 24.
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