Demonstrating soft X-ray tomography in the lab for correlative cryogenic biological imaging using X-rays and light microscopy.

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Title: Demonstrating soft X-ray tomography in the lab for correlative cryogenic biological imaging using X-rays and light microscopy.
Authors: O'Connor S; SiriusXT, 9A Holly Ave., Stillorgan Industrial Park, Blackrock, Co. Dublin, Ireland., Rogers D; SiriusXT, 9A Holly Ave., Stillorgan Industrial Park, Blackrock, Co. Dublin, Ireland., Kobylynska M; Randall Centre for Cell and Molecular Biophysics, King's College London, London, SE1 1UL, UK.; Centre for Ultrastructural Imaging, King's College London, London, SE1 1UL, UK., Geraets JA; Centre for Ultrastructural Imaging, King's College London, London, SE1 1UL, UK.; School of Life Sciences, University of Sussex, Brighton, BN1 9QG, UK., Thaysen K; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Egebjerg JM; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Brink MC; Cell Screening Laboratory, School of Biology and Environmental Science, University College Dublin, Belfield, Dublin 4, Ireland., Herbsleb L; Center of Optical Technologies, Aalen University, Aalen, Germany., Salakova M; Center of Optical Technologies, Aalen University, Aalen, Germany., Fuchs L; Center of Optical Technologies, Aalen University, Aalen, Germany., Alves F; Translational Molecular Imaging, Max-Planck-Institute of Multidisciplinary Sciences, Göttingen, Germany., Feldmann C; Institute of Inorganic Chemistry, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany., Ekman A; Department of Biological and Environmental Science and Nanoscience Centre, University of Jyväskylä, Jyväskylä, Finland., Sheridan P; SiriusXT, 9A Holly Ave., Stillorgan Industrial Park, Blackrock, Co. Dublin, Ireland., Fyans W; SiriusXT, 9A Holly Ave., Stillorgan Industrial Park, Blackrock, Co. Dublin, Ireland., McEnroe T; SiriusXT, 9A Holly Ave., Stillorgan Industrial Park, Blackrock, Co. Dublin, Ireland., O'Reilly F; SiriusXT, 9A Holly Ave., Stillorgan Industrial Park, Blackrock, Co. Dublin, Ireland.; School of Physics, University College Dublin, Belfield, Dublin 4, Ireland.; School of Biology and Environmental Science, University College Dublin, Belfield, Dublin 4, Ireland., Fahy K; SiriusXT, 9A Holly Ave., Stillorgan Industrial Park, Blackrock, Co. Dublin, Ireland., Fleck RA; Randall Centre for Cell and Molecular Biophysics, King's College London, London, SE1 1UL, UK.; Centre for Ultrastructural Imaging, King's College London, London, SE1 1UL, UK., Wüstner D; Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark., Simpson JC; Cell Screening Laboratory, School of Biology and Environmental Science, University College Dublin, Belfield, Dublin 4, Ireland., Walter A; Center of Optical Technologies, Aalen University, Aalen, Germany., Kapishnikov S; SiriusXT, 9A Holly Ave., Stillorgan Industrial Park, Blackrock, Co. Dublin, Ireland. sergey.kapishnikov@siriusxt.com.; School of Biology and Environmental Science, University College Dublin, Belfield, Dublin 4, Ireland. sergey.kapishnikov@siriusxt.com.
Source: Scientific reports [Sci Rep] 2025 Nov 27; Vol. 15 (1), pp. 45491. Date of Electronic Publication: 2025 Nov 27.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-025-29385-5