Germline polymorphisms in the immunoglobulin kappa and lambda loci underpinning antibody light chain repertoire variability.

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Title: Germline polymorphisms in the immunoglobulin kappa and lambda loci underpinning antibody light chain repertoire variability.
Authors: Engelbrecht E; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Rodriguez OL; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA.; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Lees W; Clareo Biosciences, Louisville, Kentucky, USA., Vanwinkle Z; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Shields K; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Schultze S; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Gibson WS; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Smith DR; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Jana U; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Saha S; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA., Peres A; Department of Pathology, Yale School of Medicine, New Haven, CT, USA., Yaari G; Department of Pathology, Yale School of Medicine, New Haven, CT, USA., Smith ML; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA. ml.smith@louisville.edu., Watson CT; Department of Biochemistry and Molecular Genetics, University of Louisville School of Medicine, Louisville, KY, USA. corey.watson@louisville.edu.
Source: Nature communications [Nat Commun] 2025 Nov 28; Vol. 16 (1), pp. 11707. Date of Electronic Publication: 2025 Nov 28.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-66759-9