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Enhanced Antitumor Efficacy of 225Ac-NM600 Compared to 177Lu-NM600 in Prostate Cancer Models.

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Title: Enhanced Antitumor Efficacy of 225Ac-NM600 Compared to 177Lu-NM600 in Prostate Cancer Models.
Authors: Ferreira CA; Departments of Radiology, Pharmacology and Toxicology and Biomedical Engineering, Michigan State University, East Lansing, Michigan., Potluri HK; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin., Tantawy AA; Comparative Medicine and Integrative Biology, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan., Massey CF; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Grudzinski JJ; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Carston AM; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Clemons NB; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Idrissou MB; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Thickens AS; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Rosenkrans ZT; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Choi C; Pharmaceutical Sciences Program, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin., Kerr CP; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin., Pinchuk AN; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Kwon O; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Jeffery JJ; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Bednarz BP; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin., Morris ZS; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin., Weichert JP; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., McNeel DG; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Hernandez R; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin. Electronic address: hernandez6@wisc.edu.
Source: International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2026 Jun 01; Vol. 125 (2), pp. 566-575. Date of Electronic Publication: 2025 Nov 29.
Publication Type: Journal Article; Comparative Study; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier, Inc Country of Publication: United States NLM ID: 7603616 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-355X (Electronic) Linking ISSN: 03603016 NLM ISO Abbreviation: Int J Radiat Oncol Biol Phys Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Enhanced Antitumor Efficacy of <superscript>225</superscript>Ac-NM600 Compared to <superscript>177</superscript>Lu-NM600 in Prostate Cancer Models.
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  Data: <searchLink fieldCode="AU" term="%22Ferreira+CA%22">Ferreira CA</searchLink>; Departments of Radiology, Pharmacology and Toxicology and Biomedical Engineering, Michigan State University, East Lansing, Michigan.<br /><searchLink fieldCode="AU" term="%22Potluri+HK%22">Potluri HK</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Tantawy+AA%22">Tantawy AA</searchLink>; Comparative Medicine and Integrative Biology, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan.<br /><searchLink fieldCode="AU" term="%22Massey+CF%22">Massey CF</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Grudzinski+JJ%22">Grudzinski JJ</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Carston+AM%22">Carston AM</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Clemons+NB%22">Clemons NB</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Idrissou+MB%22">Idrissou MB</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Thickens+AS%22">Thickens AS</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Rosenkrans+ZT%22">Rosenkrans ZT</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Choi+C%22">Choi C</searchLink>; Pharmaceutical Sciences Program, School of Pharmacy, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Kerr+CP%22">Kerr CP</searchLink>; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Pinchuk+AN%22">Pinchuk AN</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Kwon+O%22">Kwon O</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Jeffery+JJ%22">Jeffery JJ</searchLink>; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Bednarz+BP%22">Bednarz BP</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Morris+ZS%22">Morris ZS</searchLink>; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin; Department of Human Oncology, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Weichert+JP%22">Weichert JP</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22McNeel+DG%22">McNeel DG</searchLink>; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.<br /><searchLink fieldCode="AU" term="%22Hernandez+R%22">Hernandez R</searchLink>; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin; Departments of Medical Physics and Radiology, University of Wisconsin-Madison, Madison, Wisconsin; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin. Electronic address: hernandez6@wisc.edu.
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  Data: <searchLink fieldCode="JN" term="%227603616%22">International journal of radiation oncology, biology, physics</searchLink> [Int J Radiat Oncol Biol Phys] 2026 Jun 01; Vol. 125 (2), pp. 566-575. <i>Date of Electronic Publication: </i>2025 Nov 29.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+Inc%22">Elsevier, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7603616 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-355X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203603016%22">03603016 </searchLink><i>NLM ISO Abbreviation: </i>Int J Radiat Oncol Biol Phys <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41319721
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