IGF2BP1 fosters an immunosuppressive tumor microenvironment in high-risk neuroblastoma, contributing to their resistance to immunotherapy.

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Title: IGF2BP1 fosters an immunosuppressive tumor microenvironment in high-risk neuroblastoma, contributing to their resistance to immunotherapy.
Authors: Dhamdhere MR; Division of Pediatric Hematology and Oncology, Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, PA, USA., Gowda CP; Division of Pediatric Hematology and Oncology, Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, PA, USA., Imamura Y; Department of Neuroscience & Experimental Therapeutics, The Pennsylvania State University University College of Medicine, Hershey, PA, USA., Wang HG; Division of Pediatric Hematology and Oncology, Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, PA, USA., Schell TS; Department of Microbiology and Immunology, The Pennsylvania State University College of Medicine, Penn State Cancer Institute, Hershey, PA, USA., Spiegelman VS; Division of Pediatric Hematology and Oncology, Department of Pediatrics, The Pennsylvania State University College of Medicine, Hershey, PA, USA.
Source: Oncoimmunology [Oncoimmunology] 2025 Dec 31; Vol. 14 (1), pp. 2584408. Date of Electronic Publication: 2025 Dec 02.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
Journal Info: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101570526 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2162-402X (Electronic) Linking ISSN: 21624011 NLM ISO Abbreviation: Oncoimmunology Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2162-402X
DOI:10.1080/2162402X.2025.2584408