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Circadian rhythms and gut microbiota Dysbiosis: emerging gut-brain axis pathways in insomnia pathophysiology and Therapeutics.

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Title: Circadian rhythms and gut microbiota Dysbiosis: emerging gut-brain axis pathways in insomnia pathophysiology and Therapeutics.
Authors: Zhao D; Department of Clinical Nutrition, Shenzhen Longgang Central Hospital, Shenzhen, Guangdong, China., Zou B; Department of Clinical Nutrition, Shenzhen Longgang Central Hospital, Shenzhen, Guangdong, China., Do QL; Graduate Institute of Nutrition, China Medical University, Taichung, Taiwan; Mind-Body Interface Research Center (MBI Lab & Care), China Medical University Hospital, Taichung, Taiwan., Wu SK; Graduate Institute of Nutrition, China Medical University, Taichung, Taiwan; Mind-Body Interface Research Center (MBI Lab & Care), China Medical University Hospital, Taichung, Taiwan., Shen Y; Huada Precision Nutrition (Shenzhen) Technology Co., Ltd, Shenzhen, Guangdong, China., Yang Y; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, China; Guangdong Engineering Technology Center of Nutrition Transformation, Sun Yat-sen University, Shenzhen, Guangdong, China; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Sun Yat-sen University, Guangzhou, Guangdong, China., Kang JX; Laboratory for Lipid Medicine and Technology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA; Omega-3 and Global Health Institute, Boston, MA 02129, USA., Su KP; Mind-Body Interface Research Center (MBI Lab & Care), China Medical University Hospital, Taichung, Taiwan; College of Medicine, China Medical University, Taichung, Taiwan; Office of Research and Development, Asia University, Taichung, Taiwan; An-Nan Hospital, China Medical University, Tainan, Taiwan. Electronic address: cobol@cmu.edu.tw., Wang B; Department of Clinical Nutrition, Shenzhen Longgang Central Hospital, Shenzhen, Guangdong, China. Electronic address: yy_bwang@hotmail.com.
Source: Brain, behavior, and immunity [Brain Behav Immun] 2026 Feb; Vol. 132, pp. 106203. Date of Electronic Publication: 2025 Nov 30.
Publication Type: Journal Article; Review
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8800478 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2139 (Electronic) Linking ISSN: 08891591 NLM ISO Abbreviation: Brain Behav Immun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Circadian rhythms and gut microbiota Dysbiosis: emerging gut-brain axis pathways in insomnia pathophysiology and Therapeutics.
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  Data: <searchLink fieldCode="AU" term="%22Zhao+D%22">Zhao D</searchLink>; Department of Clinical Nutrition, Shenzhen Longgang Central Hospital, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Zou+B%22">Zou B</searchLink>; Department of Clinical Nutrition, Shenzhen Longgang Central Hospital, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Do+QL%22">Do QL</searchLink>; Graduate Institute of Nutrition, China Medical University, Taichung, Taiwan; Mind-Body Interface Research Center (MBI Lab & Care), China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Wu+SK%22">Wu SK</searchLink>; Graduate Institute of Nutrition, China Medical University, Taichung, Taiwan; Mind-Body Interface Research Center (MBI Lab & Care), China Medical University Hospital, Taichung, Taiwan.<br /><searchLink fieldCode="AU" term="%22Shen+Y%22">Shen Y</searchLink>; Huada Precision Nutrition (Shenzhen) Technology Co., Ltd, Shenzhen, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Yang+Y%22">Yang Y</searchLink>; School of Public Health (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen, Guangdong, China; Guangdong Engineering Technology Center of Nutrition Transformation, Sun Yat-sen University, Shenzhen, Guangdong, China; Guangdong Provincial Key Laboratory of Food, Nutrition and Health, Sun Yat-sen University, Guangzhou, Guangdong, China.<br /><searchLink fieldCode="AU" term="%22Kang+JX%22">Kang JX</searchLink>; Laboratory for Lipid Medicine and Technology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02129, USA; Omega-3 and Global Health Institute, Boston, MA 02129, USA.<br /><searchLink fieldCode="AU" term="%22Su+KP%22">Su KP</searchLink>; Mind-Body Interface Research Center (MBI Lab & Care), China Medical University Hospital, Taichung, Taiwan; College of Medicine, China Medical University, Taichung, Taiwan; Office of Research and Development, Asia University, Taichung, Taiwan; An-Nan Hospital, China Medical University, Tainan, Taiwan. Electronic address: cobol@cmu.edu.tw.<br /><searchLink fieldCode="AU" term="%22Wang+B%22">Wang B</searchLink>; Department of Clinical Nutrition, Shenzhen Longgang Central Hospital, Shenzhen, Guangdong, China. Electronic address: yy_bwang@hotmail.com.
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  Data: <searchLink fieldCode="JN" term="%228800478%22">Brain, behavior, and immunity</searchLink> [Brain Behav Immun] 2026 Feb; Vol. 132, pp. 106203. <i>Date of Electronic Publication: </i>2025 Nov 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8800478 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1090-2139 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208891591%22">08891591 </searchLink><i>NLM ISO Abbreviation: </i>Brain Behav Immun <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41330454
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        Value: 10.1016/j.bbi.2025.106203
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      – Code: eng
        Text: English
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            – D: 01
              M: 02
              Text: 2026 Feb
              Type: published
              Y: 2026
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