A Chronic Psoriasis Model Using Long-Term Imiquimod Application in IL-10-Deficient Mice: Recapitulating Skin Inflammation, Comorbidities, and Gut-Skin Axis Alterations.

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Title: A Chronic Psoriasis Model Using Long-Term Imiquimod Application in IL-10-Deficient Mice: Recapitulating Skin Inflammation, Comorbidities, and Gut-Skin Axis Alterations.
Authors: Kim JH; Department of Gastroenterology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea.; Seoul National University Inflammatory Bowel Disease Research Network, Seoul, Korea., Lee SR; Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea., Ahn HK; Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea., Hong HT; Department of Biomedical Sciences-Seoul National University Graduate School, Seoul, Korea., Jo UH; Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea., Im JP; Seoul National University Inflammatory Bowel Disease Research Network, Seoul, Korea.; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea., Kim JS; Seoul National University Inflammatory Bowel Disease Research Network, Seoul, Korea.; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea., Kim MJ; Department of Rheumatology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea., Lee J; Department of Nephrology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea., Park JH; Department of Pathology, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, Seoul, Korea., Park H; Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea.; Laboratory of Intestinal Mucosa and Skin Immunology, Seoul, Korea. snuhdm@gmail.com., Koh SJ; Seoul National University Inflammatory Bowel Disease Research Network, Seoul, Korea.; Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Korea.; Laboratory of Intestinal Mucosa and Skin Immunology, Seoul, Korea. jel1206@snu.ac.kr.
Source: Annals of dermatology [Ann Dermatol] 2025 Dec; Vol. 37 (6), pp. 383-396.
Publication Type: Journal Article
Journal Info: Publisher: Korean Dermatological Association Country of Publication: Korea (South) NLM ID: 8916577 Publication Model: Print Cited Medium: Internet ISSN: 2005-3894 (Electronic) Linking ISSN: 10139087 NLM ISO Abbreviation: Ann Dermatol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2005-3894
DOI:10.5021/ad.25.108