Inhibiting Glycan Degradation Prevents HIV-Induced Inflammaging and Cognitive Impairment.

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Title: Inhibiting Glycan Degradation Prevents HIV-Induced Inflammaging and Cognitive Impairment.
Authors: Giron LB; Division of Infectious Diseases, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Center for Human Immunobiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Potocsnak Longevity Institute, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Borjabad A; Icahn School of Medicine at Mount Sinai, New York, NY; USA., Hadas E; Icahn School of Medicine at Mount Sinai, New York, NY; USA., Granche J; Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA., de Menezes EGM; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Premeaux TA; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., He H; Icahn School of Medicine at Mount Sinai, New York, NY; USA., Yeung ST; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Singh S; Division of Infectious Diseases, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Center for Human Immunobiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Potocsnak Longevity Institute, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Friday C; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Glover J; University of Pennsylvania, Philadelphia, PA, USA., Balboa E; University of Pennsylvania, Philadelphia, PA, USA., Dopkin D; University of Pennsylvania, Philadelphia, PA, USA., Burrows M; University of Pennsylvania, Philadelphia, PA, USA., Secreto A; University of Pennsylvania, Philadelphia, PA, USA., Skuli N; University of Pennsylvania, Philadelphia, PA, USA., Tateno H; Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki, Japan., Denton PW; University of Nebraska Omaha, Omaha, NE, USA., Palella F; Division of Infectious Diseases, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Potocsnak Longevity Institute, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Corley MJ; University of California San Diego, San Diego, CA, USA., Ndhlovu LC; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medicine, New York, NY, USA., Norris PJ; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA., Tassiopoulos K; Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA., Volsky DJ; Icahn School of Medicine at Mount Sinai, New York, NY; USA., Abdel-Mohsen M; Division of Infectious Diseases, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Center for Human Immunobiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Potocsnak Longevity Institute, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2025 Nov 17. Date of Electronic Publication: 2025 Nov 17.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2025.11.17.688839