Enhanced antibacterial and antioxidant capabilities using indole-modified 1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile derivatives, molecular docking evaluation and in silico ADMET prediction.

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Title: Enhanced antibacterial and antioxidant capabilities using indole-modified 1-phenyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile derivatives, molecular docking evaluation and in silico ADMET prediction.
Authors: Khalaf HS; Photochemistry Department, Chemical Industries Research Institute, National Research Centre 33 El Buhouth Street, P. O. Box 12622 Cairo Egypt hematsalama2016@gmail.com ahshamroukh@yahoo.com., El-Sayed AF; Microbial Genetics Department, Biotechnology Research Institute, National Research Centre Giza Egypt.; Egypt Center for Research and Regenerative Medicine (ECRRM) Cairo Egypt., Shamroukh AH; Photochemistry Department, Chemical Industries Research Institute, National Research Centre 33 El Buhouth Street, P. O. Box 12622 Cairo Egypt hematsalama2016@gmail.com ahshamroukh@yahoo.com.
Source: RSC advances [RSC Adv] 2025 Dec 01; Vol. 15 (55), pp. 47255-47270. Date of Electronic Publication: 2025 Dec 01 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2046-2069
DOI:10.1039/d5ra07372c