Revealing the rationale behind the differential neutralization of phospholipase A2 (PLA2) enzymes in snake and bee venom by varespladib (LY-315920), a small molecule PLA2 inhibitor.
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| Title: | Revealing the rationale behind the differential neutralization of phospholipase A |
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| Authors: | Kumar R; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.; Academy of Scientific and Innovative Research, AcSIR Headquarters CSIR-HRDC Campus, Postal Staff College Area, Ghaziabad, India., Patra A; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.; Amrita Research Centre, Amrita Vishwa Vidyapeetham, Faridabad, Haryana, India., Das D; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India., Saikia K; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India., da Silva JR; LAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade De Ciências, Universidade do Porto, Porto, Portugal., Ramos MJ; LAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade De Ciências, Universidade do Porto, Porto, Portugal., Khan MR; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.; Academy of Scientific and Innovative Research, AcSIR Headquarters CSIR-HRDC Campus, Postal Staff College Area, Ghaziabad, India., Fernandes PA; LAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade De Ciências, Universidade do Porto, Porto, Portugal., Mukherjee AK; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.; Academy of Scientific and Innovative Research, AcSIR Headquarters CSIR-HRDC Campus, Postal Staff College Area, Ghaziabad, India.; Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, Assam, India. |
| Source: | Journal of biomolecular structure & dynamics [J Biomol Struct Dyn] 2025 Dec 03, pp. 1-23. Date of Electronic Publication: 2025 Dec 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Taylor & Francis Country of Publication: England NLM ID: 8404176 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-0254 (Electronic) Linking ISSN: 07391102 NLM ISO Abbreviation: J Biomol Struct Dyn Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41334682 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Revealing the rationale behind the differential neutralization of phospholipase A<subscript>2</subscript> (PLA<subscript>2</subscript>) enzymes in snake and bee venom by varespladib (LY-315920), a small molecule PLA<subscript>2</subscript> inhibitor. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kumar+R%22">Kumar R</searchLink>; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.; Academy of Scientific and Innovative Research, AcSIR Headquarters CSIR-HRDC Campus, Postal Staff College Area, Ghaziabad, India.<br /><searchLink fieldCode="AU" term="%22Patra+A%22">Patra A</searchLink>; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.; Amrita Research Centre, Amrita Vishwa Vidyapeetham, Faridabad, Haryana, India.<br /><searchLink fieldCode="AU" term="%22Das+D%22">Das D</searchLink>; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.<br /><searchLink fieldCode="AU" term="%22Saikia+K%22">Saikia K</searchLink>; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.<br /><searchLink fieldCode="AU" term="%22da+Silva+JR%22">da Silva JR</searchLink>; LAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade De Ciências, Universidade do Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Ramos+MJ%22">Ramos MJ</searchLink>; LAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade De Ciências, Universidade do Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Khan+MR%22">Khan MR</searchLink>; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.; Academy of Scientific and Innovative Research, AcSIR Headquarters CSIR-HRDC Campus, Postal Staff College Area, Ghaziabad, India.<br /><searchLink fieldCode="AU" term="%22Fernandes+PA%22">Fernandes PA</searchLink>; LAQV@REQUIMTE, Departamento de Química e Bioquímica, Faculdade De Ciências, Universidade do Porto, Porto, Portugal.<br /><searchLink fieldCode="AU" term="%22Mukherjee+AK%22">Mukherjee AK</searchLink>; Division of Life Sciences, Institute of Advanced Study in Science and Technology, Vigyan Path, Garchuk, Guwahati, Assam, India.; Academy of Scientific and Innovative Research, AcSIR Headquarters CSIR-HRDC Campus, Postal Staff College Area, Ghaziabad, India.; Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, Assam, India. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228404176%22">Journal of biomolecular structure & dynamics</searchLink> [J Biomol Struct Dyn] 2025 Dec 03, pp. 1-23. <i>Date of Electronic Publication: </i>2025 Dec 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8404176 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-0254 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207391102%22">07391102 </searchLink><i>NLM ISO Abbreviation: </i>J Biomol Struct Dyn <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41334682 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/07391102.2025.2592598 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 1 Titles: – TitleFull: Revealing the rationale behind the differential neutralization of phospholipase A2 (PLA2) enzymes in snake and bee venom by varespladib (LY-315920), a small molecule PLA2 inhibitor. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kumar R – PersonEntity: Name: NameFull: Patra A – PersonEntity: Name: NameFull: Das D – PersonEntity: Name: NameFull: Saikia K – PersonEntity: Name: NameFull: da Silva JR – PersonEntity: Name: NameFull: Ramos MJ – PersonEntity: Name: NameFull: Khan MR – PersonEntity: Name: NameFull: Fernandes PA – PersonEntity: Name: NameFull: Mukherjee AK IsPartOfRelationships: – BibEntity: Dates: – D: 03 M: 12 Text: 2025 Dec 03 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1538-0254 Titles: – TitleFull: Journal of biomolecular structure & dynamics Type: main |
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