Down-regulation of RBM47 due to diminished activation by forkhead box A1 (FOXA1) and silencing by CpG methylation is associated with epithelial-mesenchymal transition and metastasis of colorectal cancer.

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Title: Down-regulation of RBM47 due to diminished activation by forkhead box A1 (FOXA1) and silencing by CpG methylation is associated with epithelial-mesenchymal transition and metastasis of colorectal cancer.
Authors: Rokavec M; Experimental and Molecular Pathology, Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Thalkirchner Strasse 36, Munich, 80337, Germany., Du Y; Experimental and Molecular Pathology, Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Thalkirchner Strasse 36, Munich, 80337, Germany., Hermeking H; Experimental and Molecular Pathology, Institute of Pathology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Thalkirchner Strasse 36, Munich, 80337, Germany. heiko.hermeking@med.uni-muenchen.de.; German Cancer Consortium (DKTK), Partner Site Munich, Munich, 80336, Germany. heiko.hermeking@med.uni-muenchen.de.; German Cancer Research Center (DKFZ), Heidelberg, 69120, Germany. heiko.hermeking@med.uni-muenchen.de.
Source: Molecular biomedicine [Mol Biomed] 2025 Dec 03; Vol. 6 (1), pp. 133. Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Singapore Country of Publication: Singapore NLM ID: 9918283581406676 Publication Model: Electronic Cited Medium: Internet ISSN: 2662-8651 (Electronic) Linking ISSN: 26628651 NLM ISO Abbreviation: Mol Biomed Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2662-8651
DOI:10.1186/s43556-025-00382-4