Alterations in short-chain fatty acid-associated gut microbiota and tight junction integrity in adolescent major depressive disorder.

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Title: Alterations in short-chain fatty acid-associated gut microbiota and tight junction integrity in adolescent major depressive disorder.
Authors: Liu X; Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), Psychiatric Center of Chongqing Medical University the First Affiliated Hospital, Chongqing, China., Geng A; Department of Neurobiology, Basic Medical College, Chongqing Medical University, Chongqing, China., Xia M; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Lan J; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Wu H; Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), Psychiatric Center of Chongqing Medical University the First Affiliated Hospital, Chongqing, China., Zhou Z; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Huang F; Department of Neurobiology, Basic Medical College, Chongqing Medical University, Chongqing, China., He Y; Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), Psychiatric Center of Chongqing Medical University the First Affiliated Hospital, Chongqing, China., Lei T; Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), Psychiatric Center of Chongqing Medical University the First Affiliated Hospital, Chongqing, China., Hur J; Department of Biomedical Sciences, University of North Dakota, School of Medicine and Health Sciences, Grand Forks, ND, 58202, USA., Guo K; Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), Psychiatric Center of Chongqing Medical University the First Affiliated Hospital, Chongqing, China.; Department of Biomedical Sciences, University of North Dakota, School of Medicine and Health Sciences, Grand Forks, ND, 58202, USA.; Department of Neurology, University of Michigan, Ann Arbor, MI, 48109, USA., Yu X; State Key Laboratory of Genetic Engineering, School of Life Sciences, Fudan University, Shanghai, China., Zhou X; Department of Psychiatry, the First Affiliated Hospital of Chongqing Medical University, key Laboratory of Major Brain Disease and Aging Research (Ministry of Education), Psychiatric Center of Chongqing Medical University the First Affiliated Hospital, Chongqing, China. zhouxinyu@cqmu.edu.cn.
Source: Translational psychiatry [Transl Psychiatry] 2025 Dec 03; Vol. 16 (1), pp. 11. Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2158-3188
DOI:10.1038/s41398-025-03743-3