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Lack of epistatic interaction of SNCA with APOE in synucleinopathies.

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Title: Lack of epistatic interaction of SNCA with APOE in synucleinopathies.
Authors: Saini P; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 1Y2., Yu E; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 1Y2., Estiar MA; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 1Y2.; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142, USA., Krohn L; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 1Y2., Mufti K; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 1Y2., Rudakou U; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 1Y2., Ruskey JA; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada H3A 2B4., Asayesh F; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada H3A 2B4., Laurent SB; CHU Sainte Justine, University of Montreal, Montreal, Quebec, Canada H3T 1C5., Spiegelman D; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada H3A 2B4., Arnulf I; Sleep Disorders Unit, Pitié-Salpêtrière Hospital, Centre de Recherche de l'Institut du Cerveau et de la Moelle Épinière, and Sorbonne Universités, Paris 75013, France., Montplaisir JY; Centre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada H4J 1C5.; Department of Psychiatry, Université de Montréal, Montreal, Quebec, Canada H3T 1J4., Gagnon JF; Centre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada H4J 1C5.; Department of Psychology, Université du Québec à Montréal, Montreal, Quebec, Canada H2X 3JB., Desautels A; Centre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada H4J 1C5.; Department of Neurosciences, Université de Montréal, Montreal, Quebec, Canada H3C 3J7., Dauvilliers Y; National Reference Center for Narcolepsy, Sleep Unit, Department of Neurology, Gui-de-Chauliac Hospital, Centre Hospitalier Universitaire Montpellier, University of Montpellier, INSERM U1061, Montpellier 34090, France., Gigli GL; Clinical Neurology Unit, Department of Head and Neck, University Hospital of Udine, Udine 33100, Italy.; Department of Medicine (DMED), University of Udine, Udine 121 08, Italy., Valente M; Clinical Neurology Unit, Department of Head and Neck, University Hospital of Udine, Udine 33100, Italy.; Department of Medicine (DMED), University of Udine, Udine 121 08, Italy., Janes F; Clinical Neurology Unit, Department of Head and Neck, University Hospital of Udine, Udine 33100, Italy., Bernardini A; Clinical Neurology Unit, Department of Head and Neck, University Hospital of Udine, Udine 33100, Italy., Šonka K; Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital, Charles University, Prague 121 08, Czech Republic., Kemlink D; Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital, Charles University, Prague 121 08, Czech Republic., Oertel WH; Department of Neurology, Philipps University Marburg, Marburg 35032, Germany., Kaivola K; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA., Janzen A; Department of Neurology, Philipps University Marburg, Marburg 35032, Germany., Plazzi G; Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum-University of Bologna, Bologna 40126, Italy.; IRCCS-Institute of Neurological Sciences of Bologna, Bologna 40139, Italy., Antelmi E; Department of Engineering and Medicine of Innovation (DIMI), University of Verona, Verona 37134, Italy., Biscarini F; Department of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum-University of Bologna, Bologna 40126, Italy., Figorilli M; Department of Medical Sciences and Public Health, Sleep Disorder Research Center, University of Cagliari, Cagliari 09042, Italy., Puligheddu M; Department of Medical Sciences and Public Health, Sleep Disorder Research Center, University of Cagliari, Cagliari 09042, Italy., Mollenhauer B; Paracelsus-Elena-Klinik, Kassel 34128, Germany.; Department of Neurology, University Medical Center Göttingen, Göttingen 37075, Germany., Trenkwalder C; Paracelsus-Elena-Klinik, Kassel 34128, Germany.; Department of Neurology, University Medical Center Göttingen, Göttingen 37075, Germany., Sixel-Döring F; Department of Neurology, Philipps University Marburg, Marburg 35032, Germany.; Paracelsus-Elena-Klinik, Kassel 34128, Germany., Cochen De Cock V; Sleep and Neurology Unit, Beau Soleil Clinic, Montpellier 34070, France.; EuroMov Research Laboratory, University of Montpellier, Montpellier 34090, France., Monaca CC; Department of Clinical Neurophysiology and Sleep Center, University of Lille Nord de France, Centre Hospitalier Universitaire Lille, Lille 59045, France., Heidbreder A; Department of Neurology and Clinical Research Institute for Neuroscience, Johannes Kepler University Linz, Linz 4020, Austria., Ferini-Strambi L; Department of Neurological Sciences, Università Vita-Salute San Raffaele, Milan 20132, Italy., Dijkstra F; Laboratory for Sleep Disorders, Sint-Dimpna Regional Hospital, Geel 2440, Belgium.; Department of Neurology, Sint-Dimpna Regional Hospital, Geel 2440, Belgium.; Department of Neurology, University Hospital Antwerp, Edegem, Antwerp 2650, Belgium., Viaene M; Laboratory for Sleep Disorders, Sint-Dimpna Regional Hospital, Geel 2440, Belgium.; Department of Neurology, Sint-Dimpna Regional Hospital, Geel 2440, Belgium., Abril B; Sleep Disorder Unit, Carémeau Hospital, Centre Hospitalier Universitaire Nîmes, Nîmes 30029, France., Boeve BF; Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA., Postuma RB; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada H3A 2B4., Rouleau GA; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 1Y2., Anselmi V; National Reference Center for Narcolepsy, Sleep Unit, Department of Neurology, Gui-de-Chauliac Hospital, Centre Hospitalier Universitaire Montpellier, University of Montpellier, INSERM U1061, Montpellier 34090, France., Ibrahim A; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck 6020, Austria., Stefani A; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck 6020, Austria., Högl B; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck 6020, Austria., Hu MTM; Oxford Parkinson's Disease Centre, University of Oxford, Oxford OX1 3QX, UK.; Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford OX3 9DU, UK., Scholz SW; Neurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA., Gan-Or Z; Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada H3A 1Y2.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada H3A 2B4.
Source: Brain communications [Brain Commun] 2025 Nov 17; Vol. 7 (6), pp. fcaf455. Date of Electronic Publication: 2025 Nov 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2632-1297
DOI:10.1093/braincomms/fcaf455