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Hepatic Effects, Potential Drug-Induced Liver Injury, and Other Liver Safety Considerations of Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in the New Era of Expanding Non-oncology Indications: Literature Review and Expert Consensus.

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Bibliographic Details
Title: Hepatic Effects, Potential Drug-Induced Liver Injury, and Other Liver Safety Considerations of Chimeric Antigen Receptor T-Cell (CAR-T) Therapy in the New Era of Expanding Non-oncology Indications: Literature Review and Expert Consensus.
Authors: Fettiplace A; AstraZeneca, Cambridge, UK. anna@fettiplaceconsulting.com., Regev A; Eli Lilly and Company, Indianapolis, USA., Kiazand A; AstraZeneca, Cambridge, USA., Heinzel-Pleines U; Bayer Pharmaceuticals, Leverkusen, Germany., Bahjat M; Immunology Safety, Biopharmaceuticals R&D, AstraZeneca, Cambridge, UK., Garg A; Sanofi, Patient Safety and Pharmacovigilance, Morristown, NJ, USA., Kikuchi L; Bayer, SA, São Paulo, Brazil., Li H; Global Medical Safety, Johnson & Johnson, New Brunswick, NJ, USA., Hamidi A; Amgen, Thousand Oaks, USA., Alpers DH; Department of Medicine, Washington University School of Medicine, St Louis, MO, USA., Tillmann H; Division Gastroenterology, Hepatology and Nutrition, East Carolina University, Greenville, NC, USA., Larrey D; Liver Unit, Saint Eloi Hospital, Montpellier School of Medicine, Montpellier, France., Di Bisceglie AM; Saint Louis University, St. Louis, MO, USA., Lewis JH; Georgetown University Hospital, Washington, DC, USA.
Source: Drug safety [Drug Saf] 2026 Jun; Vol. 49 (6), pp. 631-654. Date of Electronic Publication: 2025 Dec 04.
Publication Type: Consensus Statement; Journal Article; Review
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9002928 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1942 (Electronic) Linking ISSN: 01145916 NLM ISO Abbreviation: Drug Saf Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1179-1942
DOI:10.1007/s40264-025-01635-5