Benzo[a]pyrene exacerbates allergen-induced airway inflammation through NLRP3-dependent dendritic cell activation and pathogenic T helper cell polarization.

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Title: Benzo[a]pyrene exacerbates allergen-induced airway inflammation through NLRP3-dependent dendritic cell activation and pathogenic T helper cell polarization.
Authors: Zou H; Department of Otolaryngology of Longgang Central Hospital & Clinical Collage of Guangzhou University of Chinese Medicine, Shenzhen, China.; Institute of Allergy & Immunology of Shenzhen University, State Key Laboratory of Respiratory Diseases Allergy Division at Shenzhen University, and Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen, China., Duan J; Department of Otolaryngology of Longgang Central Hospital & Clinical Collage of Guangzhou University of Chinese Medicine, Shenzhen, China.; Institute of Allergy & Immunology of Shenzhen University, State Key Laboratory of Respiratory Diseases Allergy Division at Shenzhen University, and Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen, China., Xie Y; Department of Otolaryngology of Longgang Central Hospital & Clinical Collage of Guangzhou University of Chinese Medicine, Shenzhen, China.; Institute of Allergy & Immunology of Shenzhen University, State Key Laboratory of Respiratory Diseases Allergy Division at Shenzhen University, and Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen, China., Chen R; Department of Otolaryngology of Longgang Central Hospital & Clinical Collage of Guangzhou University of Chinese Medicine, Shenzhen, China.; Institute of Allergy & Immunology of Shenzhen University, State Key Laboratory of Respiratory Diseases Allergy Division at Shenzhen University, and Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen, China., Ye Y; Institute of Allergy & Immunology of Shenzhen University, State Key Laboratory of Respiratory Diseases Allergy Division at Shenzhen University, and Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen, China., Zhang A; Department of Critical Care Medicine, Second Hospital of Shanxi Medical University, Taiyuan, China., Yang P; Institute of Allergy & Immunology of Shenzhen University, State Key Laboratory of Respiratory Diseases Allergy Division at Shenzhen University, and Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen, China., Yang G; Department of Otolaryngology of Longgang Central Hospital & Clinical Collage of Guangzhou University of Chinese Medicine, Shenzhen, China., Liu X; Institute of Allergy & Immunology of Shenzhen University, State Key Laboratory of Respiratory Diseases Allergy Division at Shenzhen University, and Shenzhen Key Laboratory of Allergy & Immunology, Shenzhen, China.
Source: Frontiers in immunology [Front Immunol] 2025 Nov 19; Vol. 16, pp. 1699886. Date of Electronic Publication: 2025 Nov 19 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1699886