Sequential release of bioactive factors from functionalized metal-organic framework hydrogel enhances interfacial osseointegration of 3D-printed titanium alloy porous scaffolds.

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Title: Sequential release of bioactive factors from functionalized metal-organic framework hydrogel enhances interfacial osseointegration of 3D-printed titanium alloy porous scaffolds.
Authors: Che Z; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China., Sheng X; Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Wuxing, Huzhou, Zhejiang 313000, P. R. China., Wu Y; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China., Lin B; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China., Song K; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China., Chen Q; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China., Chen A; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China., Deng L; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China., Chen J; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China., Cai M; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.
Source: Theranostics [Theranostics] 2026 Jan 01; Vol. 16 (2), pp. 852-875. Date of Electronic Publication: 2026 Jan 01 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
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  Data: Sequential release of bioactive factors from functionalized metal-organic framework hydrogel enhances interfacial osseointegration of 3D-printed titanium alloy porous scaffolds.
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  Data: <searchLink fieldCode="AU" term="%22Che+Z%22">Che Z</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.<br /><searchLink fieldCode="AU" term="%22Sheng+X%22">Sheng X</searchLink>; Huzhou Central Hospital, Fifth School of Clinical Medicine of Zhejiang Chinese Medical University, Wuxing, Huzhou, Zhejiang 313000, P. R. China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.<br /><searchLink fieldCode="AU" term="%22Lin+B%22">Lin B</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.<br /><searchLink fieldCode="AU" term="%22Song+K%22">Song K</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.<br /><searchLink fieldCode="AU" term="%22Chen+A%22">Chen A</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.<br /><searchLink fieldCode="AU" term="%22Deng+L%22">Deng L</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.<br /><searchLink fieldCode="AU" term="%22Cai+M%22">Cai M</searchLink>; Department of Orthopaedics, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, No.301 Middle Yanchang Road, Shanghai 200072, P. R. China.
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  Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2026 Jan 01; Vol. 16 (2), pp. 852-875. <i>Date of Electronic Publication: </i>2026 Jan 01 (<i>Print Publication: </i>2026).
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        Value: 10.7150/thno.120711
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            – D: 01
              M: 01
              Text: 2026 Jan 01
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