Loss of Parkinson Disease Protein 7 (PARK7) upregulates ROS and cell migration and is associated with recurrent pregnancy loss.

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Title: Loss of Parkinson Disease Protein 7 (PARK7) upregulates ROS and cell migration and is associated with recurrent pregnancy loss.
Authors: Yang Z; Department of Women's Health, University Hospital Tübingen, Calwerstraße 7/6, 72076, Tübingen, Germany., Hellwich E; Institute of Applied Physics, University of Tübingen, Tübingen, Germany., Rafiq NM; Interfakultäres Institut Für Biochemie, University of Tübingen, Tübingen, Germany., Joselin A; Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada., Im DS; Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada., Kaushik G; Department of Clinical Neurosciences, Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary, Calgary, Canada., Singh Y; Department of Women's Health, University Hospital Tübingen, Calwerstraße 7/6, 72076, Tübingen, Germany.; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany., Mulac-Jericevic B; Department of Physiology and Immunology, Medical School, University of Rijeka, Rijeka, Croatia., Jiang H; Reproductive Medicine Center, Department of Obstetrics and Gynecology, the First Affiliated Hospital of Anhui Medical University, Hefei, China., Gonzalez-Menendez I; Institute of Pathology and Neuropathology, Comprehensive Cancer Center, University Hospital Tübingen, Tübingen, Germany.; Core Facility Histology, Faculty of Medicine Tübingen, University Hospital Tübingen, Tübingen, Germany., Quintanilla-Martinez L; Institute of Pathology and Neuropathology, Comprehensive Cancer Center, University Hospital Tübingen, Tübingen, Germany.; Core Facility Histology, Faculty of Medicine Tübingen, University Hospital Tübingen, Tübingen, Germany.; Cluster of Excellence iFIT (EXC2180) 'Image-Guided and Functionally Instructed Tumor Therapies, University of Tübingen, Tübingen, Germany., Brucker SY; Department of Women's Health, University Hospital Tübingen, Calwerstraße 7/6, 72076, Tübingen, Germany., Schäffer TE; Institute of Applied Physics, University of Tübingen, Tübingen, Germany., Salker MS; Department of Women's Health, University Hospital Tübingen, Calwerstraße 7/6, 72076, Tübingen, Germany. madhuri.salker@med.uni-tuebingen.de.; Department of Obstetrics and Gynecology, Faculty of Medicine, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. madhuri.salker@med.uni-tuebingen.de.; Women's Health Research Institute, Vancouver, BC V6H 3N1, Canada. madhuri.salker@med.uni-tuebingen.de.; BC Children's Hospital Research Institute, Vancouver, British Columbia, BC V5Z 4H4, Canada. madhuri.salker@med.uni-tuebingen.de.
Source: Molecular medicine (Cambridge, Mass.) [Mol Med] 2025 Dec 05; Vol. 32 (1). Date of Electronic Publication: 2025 Dec 05.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 9501023 Publication Model: Electronic Cited Medium: Internet ISSN: 1528-3658 (Electronic) Linking ISSN: 10761551 NLM ISO Abbreviation: Mol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1528-3658
DOI:10.1186/s10020-025-01344-w