Dopaminergic tone inhibits spontaneous glutamate release and augments homeostatic synaptic plasticity.

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Title: Dopaminergic tone inhibits spontaneous glutamate release and augments homeostatic synaptic plasticity.
Authors: Uzay B; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37240-7933, USA. burak.uzay@mountsinai.org.; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37240-7933, USA. burak.uzay@mountsinai.org.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. burak.uzay@mountsinai.org.; Nash Family Department of Neuroscience, Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA. burak.uzay@mountsinai.org., Zhang KJ; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37240-7933, USA.; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37240-7933, USA., Monteggia LM; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37240-7933, USA.; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37240-7933, USA., Kavalali ET; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37240-7933, USA. ege.kavalali@vanderbilt.edu.; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37240-7933, USA. ege.kavalali@vanderbilt.edu.
Source: Molecular psychiatry [Mol Psychiatry] 2026 Apr; Vol. 31 (4), pp. 2283-2297. Date of Electronic Publication: 2025 Dec 06.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Specialist Journals Country of Publication: England NLM ID: 9607835 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5578 (Electronic) Linking ISSN: 13594184 NLM ISO Abbreviation: Mol Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5578
DOI:10.1038/s41380-025-03374-6